anglické - Centrum pro výzkum toxických látek v prostředí
Transkript
anglické - Centrum pro výzkum toxických látek v prostředí
2014 YEARBOOK RESEARCH CENTRE FOR TOXIC COMPOUNDS IN THE ENVIRONMENT RECETOX LEARN DISCOVER PROVE APPLY Contents chapter One chapter eight chapter Two chapter Nine Introduction4 Organizational Structure and Management of the RECETOX Centre chapter Three Financial Resources chapter Four Research Infrastructure chapter Five Human Resources chapter six 6 8 10 12 Education16 chapter seven Research20 Publication and Other Outputs 26 Social and Environmental Responsibility 32 in the media and awards 34 chapter ten chapter eleven Conclusions36 chapter twelve Glossary of Terms38 Annexes40 chapter One Introduction is 2014 yearbook describes the life of the Research Centre for Toxic Compounds in the Environment (hereaer the “RECETOX Centre”) operating within the Faculty of Science, Masaryk University, Brno, Czech Republic. e RECETOX was established on March 1 2010 with support of the CETOCOEN project (no. CZ.1.05/2.1.00/01.0001) from the European Regional Development Fund, Operational Programme „Research and Development for Innovations“, Priority Axis 2 (OP RDI). e Centre entered a five-year sustainability period in January 2014. It is supported by a project from the Ministry of Education, Youth and Sports of the Czech Republic within the National Sustainability Programme. It is our time to prove that previous investments into excellent science were used well. And, as we collect the fruits of previous endeavours, we need also plant new fields for the future at the same time. is yearbook describes a number of achievements of the RECETOX Centre. For example, the RECETOX research infrastructure successfully maintained its place on the Czech Roadmap of Large Research infrastructures in the two-round international evaluation. In addition, the Trace Analytical Laboratories, a core unit of research infrastructure with the largest share of projects, orders and external users, was certified. e Czech Institute for Accreditation issued an accreditation certificate for the performance of chemical analyses of food, feeds, biological material and environmental samples and to analyze organochlorine pesticides, dibenzodioxins and furans, dioxin-like and indicator polychlorinated biphenyls and polybrominated diphenyl ethers. All that further promoted interest of international partners in the use of our laboratory facilities and the expertise therein. Moreover, two research contracts were commissioned by the United Nations Environment Programme (UNEP). One was to support the international monitoring network MONET in Africa to collect environmental samples of air, water and soils and analyze toxic chemicals therein and the other to build a global electronic database and web portal for the worldwide collection of data on persistent organic pollutants in the environment based on experience gained from the development of the GENASIS environmental database. Furthermore, the first stage of the development of new online portal on South Moravian data from the WHO European Longitudinal Study of Pregnancy and Childhood (ELSPAC) was completed in 2014. ELSPAC data are already in use by researchers, and they are also available online to the general public in both Czech and English. In addition, a successful project proposal, CETOCOEN plus, was submi¡ed to the operational programme call (OP RDI 2.1) in early 2014 to support further development of interdisciplinary research teams and further use of epidemiological data. Despite the subsequent cancellation of the call by its provider, the project is now being implemented and supported by Masaryk University itself. Several international researchers arrived at RECETOX in 2014 thanks to support granted by the SOMOPRO projects, providing the opportunity to establish their career. We have also enhanced cooperation with our Czech partners including those at Masaryk University. Our research teams bid successfully for new projects from the Czech Science Foundation and the Technology Agency of the Czech Republic, as well as international projects from Norwegian Funds supporting cooperation and international mobility of researchers. Finally, both scientists and students in the Centre were awarded for their research, excellent projects and results at multiple occasions. Publications in the top international peer-reviewed journals in our field as well as acceptance of international patents are also a positive evaluation of the work of our staff. I hope that these good achievements above will further inspire us, lead to new ideas and open doors to new cooperation. I wish you all the success and stamina for 2015 Professor Jana Klánová, Ph.D Director of the RECETOX Centre 5 chapter Two Organizational Structure and Management of the RECETOX Centre e RECETOX Centre is an independent department of the Faculty of Science, Masaryk University. Its current organizational structure with the integrated management structure is shown in an organigramme in Annex 1. e director of the RECETOX Centre is its top representative. Her responsibilities and rights are laid down by the Statute and Organizational Rules of the Faculty of Science Masaryk University. She is responsible in particular for the long-term strategy of the RECETOX Centre, human resources policy, quality of education and research and housekeeping/financial management. She directs the Centre with assistance of the Executive Board consisting of her deputies for education, research, finance, technical and administrative operations, coordinator of the research infrastructure and director of application (national and regional) centres. e composition of the Executive Board is provided in Annex 1. At present, the Centre is composed of four research programmes, three core research infrastructure facilities and two application bodies, in line with its Organizational Rules. All research and application units are supported by the Centre’s well-established effective and efficient management team. 1. environmental chemistry and modelling 2. organic photochemistry and supramolecular chemistry 3. protein engineering 4. ecotoxicology Research programme leaders are members of an advisory body to the RECETOX Centre Director – the Kolegium. is body meets in both standard and extended form throughout the year. e composition of the Kolegium in both its forms is provided in Annex 1. e state of the art research infrastructure of the RECETOX Centre is effectively distributed among research teams; in addition, some infrastructure has been centralized in three core facilities: 1. trace analytical laboratories 2. genasis information system 3. epidemiological database of the elspac longitudinal study RECETOX research infrastructure has been included in the Czech Roadmap of Large Infrastructures for Research, Development and Innovation endorsed by the Czech government in 2010. e core facilities of the infrastructure provide support to the RECETOX research programmes, perform own research projects, and are also openly accessible to the external research community, both nationally and internationally. RECETOX also serves as the National Centre for Toxic Compounds and the Stockholm Convention Regional Centre for Capacity-building and the Transfer of Technology. As such, these two units of the RECETOX Centre use outputs from research teams and infrastructure to facilitate collaboration with stakeholders from governments and industry to transform our research into practical applications and make the best and most effective use of both the instrumental and human capacity of the RECETOX Centre. 7 chapter Three Financial Resources e span and structure of financial resources for the RECETOX Centre during 2010–2014 is shown in Figure 1 below (current assets only). e current assets reached 170 million CZK in 2014. e increase in budgets from 2010 onwards is linked to the implementation of the OP RDI project CETOCOEN and two OP Education for Competitiveness (OP EC) projects. However, Figure 1 also demonstrates that the OP projects are responsible for only about half of the increase; the other half is linked to increased effectiveness in mobilizing funding from other sources. A part of the current assets from OP RDI is also a current asset for the construction of the RECETOX Centre’s pavilion and of its equipment; that, however, is one-off cost that will not be repeated in coming years. In addition, capital assets need to be added to the current assets to obtain the final figure; the capital assets ranged from 100 to 200 million CZK per year during the implementation of the OP RDI project (and were predominantly spent on construction and equipment for the RECETOX Centre pavilion). In 2014 almost 25.4 million CZK of financial resources of the RECETOX Centre came from the educational support for providing courses and teaching. An additional 6.3 million CZK of institutional support was for specific research of Ph.D. students. ese two represent 13.1% and 21.1% of the total income of the RECETOX Centre. Institutional support for research programmes reached An additional 59 million CZK were mobilized from specific project funding and from contract research; i.e. 28.4 million CZK were provided through national projects (7 million CZK for the development of the research infrastructure), 20.9 million CZK from international projects, 3.9 million CZK from national contract research and 4.2 million CZK from international contract research. Due to the character of our research, the contract research funding comes mainly from public sector funding sources. With regards to the structure of the resources apart from operational programmes, 55% was institutional support, 22% was national and 16% was international project funding, and 6% was contract research. e ratio of specific funding from national and international projects reached 4:3 and for contract research 1:1 between national and international contract research. e current assets from the National Sustainability Programme project reached 34 million CZK and human resources support reached 6.7 million CZK from the resources of the OP EC (OPVK) projects. 200 mil. CZK financial resources, current assets only, in CZK Figure 1. Financial resources of the RECETOX Centre in 2010–2014 (in Czech Crowns, CZK, current assets only) 39.2 million CZK and, consequently, the total institutional support reached over 72 million CZK in 2014. National Sustainability Programme 150 mil. CZK OP RDI (OPVaVpI) OP EC (OPVK) Contract research – international 100 mil. CZK Contract research – CZ International research projects National research projects Institutional support – specific research 50 mil. CZK Institutional support – publications Institutional support – research programme 0,00 CZK 2010 Education support 2011 2012 year 2013 2014 9 chapter Four Research Infrastructure e RECETOX research infrastructure provides facilities and support for basic and applied research for the research programmes of the Centre, for laboratory and field studies and experiments, and for long-term monitoring programs. e infrastructure consists of three core units – the Trace Analytical Laboratories, the GENASIS information system, and the epidemiological database of the ELSPAC longitudinal study. e instrumentation of the RECETOX infrastructure is distributed between the three units above, as well as in individual research programs. In addition, the research infrastructure is also openly accessible to both national and international external research communities and it also supports implementation of student research projects at Ph.D, master, and bachelor levels. External users/applicants interested in the use of research infrastructure (RI) of the Centre are recruited by a permanent open-call to submit research projects. e applicants are requested to submit three documents: a filled application form accompanied by the curriculum vitae of the applicant, motivation le¡er briefly describing the proposed research topic, experiments, and expected outcomes and a recommendation le¡er. All applications are evaluated in a two-stage process. e first round examines the technical feasibility of the proposed project in the RECETOX RI and in the second round the scientific excellence is evaluated by an expert panel. Final approval of the proposal is confirmed by the Kolegium (see chapter 2). All applicants are informed of the outcome of the evaluation process within three months of submission of the proposal. Communication with successful applicants starts immediately aer the Kolegium‘s decision to determine dates of their stay. More detailed information and application forms are available on the website of the research infrastructure: www.recetox.muni.cz/RI utilization of the recetox research infrastructure in 2014 Approximately 20% of the capacity of the RECETOX research infrastructure has been made available to external users; the majority of those users are from abroad (78%). ey are from institutions cooperating with the RECETOX Centre over a longer term in the implementation of international research projects, but also from new institutions, industry partners, and national or regional authorities. A total of 40 requests for access to RECETOX research infrastructure were submi¡ed in 2014. Based on the assessment of the intended scientific added value, time and finance allocation needed to cover access to the infrastructure, 68% of the requests received approval. In 2014, the RECETOX research infrastructure hosted 27 researchers (21 international ones) for 40 person months at the Centre. 79% of them were from universities, 14% from research institutes, and 7% from the private sector. An additional 69 students working on their bachelor degree papers, 74 students finalizing their masters degrees and 77 students performing research for their doctoral theses used RECETOX research infrastructure in 2014; 22 out of 77 Ph.D. students work collaboratively on their Ph.D; they perform it in a combined study programme, as they are simultaneously a student in the RECETOX Centre and staff of a third party organization (application sector). In 2014, the research infrastructure was strengthened by new equipment and facilities using an investment from the National Sustainability Programe project. A detailed overview of the instrumentation available and its location is provided in the RECETOX Centre brochure, in the 2013 RECETOX yearbook, and on the RECETOX website. 11 chapter Five Human Resources By end of 2014, there were 103 researchers and 16 managers (a total of 119 research staff). An additional 25 staff provide administrative and technical support. A total of 174 employees, included 88 women (50% of the total) and 23 international staff (13%) used the 127.08 full time equivalents (FTE) available at the RECETOX Centre. e average age of staff was 35 years. e full list of RECETOX Centre staff is in Annex 2. As shown in Figure 2, there were 22 (16.4 FTE) academic staff: 9 (6.4 FTE) professors, 6 (4.8 FTE) associate professors, and 7 (5 FTE) assistant professors. Researchers are supported by 19 (17.5 FTE) technical staff in the research infrastructure or individual research programmes and by 20 (19.3 FTE) project, economic support, administrative and technical support staff, including management. erefore, a total of 39 staff (36.8 FTE) provides research support, representing of a third of all FTEs. Furthermore, there are 103 researchers in the Centre consisting of 22 long term staff (11.8 FTE), 25 post-doctoral fellows (24 FTE) and 47 Ph.D. students with a part time contract (a total of 25.7 FTE). Figure 2. Positions and age structure of the RECETOX Centre in 2010–2014 (in FTE, full time equivalent) 130 Amount of staff in FTE 120 110 nonqualified staff 100 administrative staff 90 technical staff 80 researcher over 60 years researcher 50-59 years 70 researcher 40-49 years 60 researcher 30-39 years 50 researcher 29 years 40 assistant professor 30 associate professor 20 professor 10 0 2010 2011 2012 2013 2014 Figure 3 shows the long-term (five-year) development in the staff size. e total staff gradually increased due to the implementation of an increasing number of European operational programme projects and international projects, in particular through implementation of the CETOCEN project. e increase observed in 2014 was due to opening of a new research field and recruitment of its project team (16 people). As shown in Figures 3 and 4, the share of international staff reached a peak of 23% of all staff between 2010–2013. However, this share dropped to 13% in 2014 as some projects supported from operational programs came to a close. It is also evident that Brno is not a final destination for a majority of international researchers who leave, in particular for family reasons, aer having spent here two to three years. While the facilities, quality of the research, and research support of the RECETOX Centre a¡ract international staff, their departure is usually caused by insufficient readiness of regional infrastructure (no quality English schools, low non-Czech language proficiency in services and health care) as well as the unse¡led future of the Czech research policy. International scientists from 13 Australia, Belarus, Canada, Chile, Congo, Finland, France, Germany, Greece, India, Indonesia, Italy, Netherlands, Pakistan, Poland, Russian Federation, Slovakia, South Korea, Spain, and Sweden worked with us in 2014. Figure 4 shows that 50.6% of all FTE are held by women. e RECETOX Centre management also actively supports the return of mothers to work aer maternity leave through a project supported by operational programme human resources (OP LZZ) as shown in more detail in Chapter 9 of this yearbook. e management of the RECETOX Centre systematically creates conditions and possibilities for further development of its employees based on their individual career plans. e increase in expertise of both junior and senior research staff is also supported by programmes for international mobility used for study/ Figure 3. Staff increase in the RECETOX Centre over the 2010–2014 period research visits to top international institutes. e RECETOX Centre can use the following instruments: Operation Programme Education for Competitiveness (OPVK), AMVIS/KONTAKT projects that support collaboration with universities in USA (three projects); and Marie Curie Fellowships (one project), COST programme or DBU or SCIEX scholarships within the EU. All these funding sources provide financial support for travel and research stays abroad to work with leading scientific teams. Moreover, a¡racting international scientists or re-integration of the Czech scientists from abroad is supported by the South Moravian region through SoMoPro grants; RECETOX held three projects in 2014. A total of 198 research trips and study visits took place abroad in 2014 (97 staff of the RECETOX Centre). Figure 4. Development and changes in the RECETOX human resources structure and share of international staff (percentage) in 2010–2014 men % total women total international 54.8 53.6 174 46.4 154 women % 45.2 48.0 international staff % 52.0 50.6 49.4 49.4 50.6 123 84 69 64 38 32 2010 14 2011 2012 2013 22.0 22.1 13.2 13.1 34 27 11 5 88 76 23 2014 7.2 2010 2011 2012 2013 2014 Water Sampling 15 chapter six Education e RECETOX Centre provides university education in Masaryk University’s Faculty of Science at all three levels of higher education: bachelor (BSc), master (MSc) and doctoral (Ph.D.). study majors All bachelor and master majors are accredited until 2018 for daily studies in Czech. Doctoral degree in Environmental Chemistry and Ecotoxicology are also accredited until 2018, for both daily and combined programmes (combined programme = study and work at the same time) and can be provided in Czech or English. As the accreditation of the professorship (habilitation) for Environmental Chemistry is valid until 2015, an extension of that period was requested in the end of 2014. A new request for professorship in Ecotoxicology as the second principal field of the Centre was also submi¡ed. majors guaranteed by recetox ecotoxicology within the special biology major, bachelor degree in experimental biology computational biology major, bachelor degree in experimental biology environmental chemistry major, master degree in chemistry ecotoxicology within the special biology major, masters degree in experimental biology computational biology major, master degree in experimental biology environmental chemistry major, doctoral degree in chemistry ecotoxicology major, doctoral degree in biology 17 Figure 5. Quantity and distribution of graduates in 2014 in majors supervised by the RECETOX Centre 75 73 57 24 total 36 47 46 33 Bc MSc 22 21 32 33 29 PhD 18 13 9 8 6 8 6 Bc – EKOT 22 11 13 5 5 9 3 12 6 10 9 13 2 6 10 13 7 Bc – BIMAT 9 12 12 9 10 10 13 10 MSc – EKOT MSc – CHŽP MSc – BIMAT 2010 2011 2012 2013 2014 students and graduates e RECETOX Centre admi¡ed 70 new students to its majors in 2014 (Ecotoxicology: 16 bachelor degree, 6 master degrees, and 6 doctoral degrees, Computational Biology: 19 bachelor degree and 8 master degree, and Environmental Chemistry: 10 master degree and 5 doctoral degrees). A grand total of all students in majors supervised by the RECETOX Centre reached 198 in 2014. 18 Work on 77 doctoral theses was ongoing in 2014 with two thirds being daily study programme students. In addition, 60 students have successfully completed their studies, passed exams and defended their papers/theses and graduated from the RECETOX Centre’s majors in 2014 – 19 Bachelors, 33 Masters and 8 Ph.D. In addition, a further 15 graduates ( bachelors) majoring in chemistry have prepared their paper at the RECETOX Centre. Several papers were prepared and defended in English (one master and two Ph.D. papers). A full list of graduates in 2014 is available in Annex 3; the structure of graduates is provided in Figure 5. teachers/lecturers Out of 24 academic staff of the Centre there are 9 professors (1 woman), 6 associate professors (1 woman) and 7 assistant professors (3 women), 1 assistant and one research specialist in 2014. For more details see Annex 2. Overall, a total of 59 RECETOX staff (15 women) have been involved in the education process in 2014. classes and courses e Centre provided 75 courses, classes, lectures, and seminars; 16 out of 75 were laboratory, field or IT exercise and practical classes. Moreover, there were five regular presentation workshops organized by majors each week. About two thirds of the courses are lectures and courses on various aspects of environmental chemistry, environmental analysis, ecotoxicology, toxicology and ecology. e remaining third of all courses focus on analyses of medical and environmental data and modelling, and are given in cooperation with the Institute of Biostatistics and Analyses of Masaryk University (IBA MU). Eight of the aforementioned courses were taught in English. work with talented students An inextricable part of the RECETOX Centre’s educational activities is a systematic support for and cooperation with talented secondary school students. is continued in 2014 through the interdisciplinary N-trophy contest for secondary students (280 participants competed in biology, chemistry, physics and logic), a special course for Young Scientists – Knowing Nature (200 participants), and a number of excursions for secondary schools from across the Czech Republic to our laboratories throughout 2014 (60 students). Moreover, the RECETOX Centre cooperated with the Czech Academy of Science in the “Open Science” project that provides further training to teachers of natural sciences and trains them in using modern equipment, methods, and experimental approaches that can be employed in the secondary school curricula. e RECETOX Centre organized a fully booked week-long course for 20 teachers that consisted of both lectures and experimental and practical courses and training. Last but not least, the Centre also prepared and provided activities and events for general public through open door days, science festivals, and contests (Science Café, Science Slam, Day of Science, Night of Scientists and other events). Overall, about 5000 people became acquainted with our work. An overview of the educational and awareness raising activities organized by the Centre is available in Annex 7. In addition, the RECETOX Centre published a new e-textbook and one statistical functions library for R-language. More details are given in Annex 5. 19 chapter seven Research is part of the yearbook provides an overview on research projects and contract research, including a list of the most significant results. A more detailed description and analysis of the publications published in 2014 is given in chapter 8 and the full list and citations are given in Annex 5. research projects in 2014 e RECETOX Centre undertook 48 research projects (ten international and 38 national) in 2014. Financial support has been obtained from 12 subjects and within 23 funding programs (eight international and 15 national ones). e RECETOX Centre participated in three FP7 projects (isoSoil, ArcRisk, AquaRehab, EuroEcotox, REFORM, and DENAMIC), and one FP7 Marie Curie International Training Network for young scientists (CSI Environment). In addition, the Centre has implemented two EU Interregional cooperation projects (OP CZ-Austria and OP CZ-Slovakia), three AMVIS/KONTAKT projects supporting collaboration with US universities, and three projects SoMoPro provided by the South Moravian Region supporting distinguished international researchers to se¡le in institutions of South Moravia. Table 1. Providers of research projects and number of such projects held by the Centre in 2014 international research projects Table 1 lists funding providers for research grants; a full list of projects undertaken by the RECETOX Centre in 2014 is provided in Annex 4. national research projects NATIONAL RESEARCH PROJECTS Ministry of Education / Operational Programme Education for Competitiveness (OPVK) 1 Ministry of Education / Large Research Infrastructures for Research, Development and Innovation 1 Ministry of Education / National Sustainability Programme I (LO) 1 Ministry of Education / KONTAKT II (projects starting 2011 the earliest) – AMVIS 3 Ministry of Education / national support for FP7 projects (2007–2013) 3 Ministry of Education / Fund for University Development 1 Czech Science Foundation / Standard projects 9 Czech Science Foundation / Post-doctoral grants 2 European Union / FP7 3 Technology Agency of the Czech Republic / BETA programme 3 European Union / FP7 / Marie Curie International Training Network 1 Technology Agency of the Czech Republic / ALFA programme 1 European Union / TEMPUS 1 Ministry of Interior of the Czech Republic / Program of security research 2010–2015 1 European Union/ Other community programs 1 Ministry of Agriculture of the Czech Republic / Research in the agriculture complex (VAK) 1 European regional cooperation Germany-Czech Republic 2007–2013 (OP Czech Republic – Austria and OP Czech Republic – Slovakia) 1 South Moravia Region / SoMoPro 3 Ministry for Regional Development (OP Czech Republic – Slovakia) 1 Masaryk University / Student projects support 7 World Health Organization, European Centre for Environment and Health 1 Masaryk University / Research Support Programme 1 American Jewish Joint Foundation 1 grand total 48 21 results of the research in 2014 is chapter provides an overview of the most significant results a¡ained by researchers of the RECETOX Centre in 2014. Table 2 below provides a closer look at papers listed in this chapter, including quality indicators in relation to other outputs in the field (impact factor (IF) and the percentile, defining in percentage the ranking of the journal within its own scientific field). A full list of all publications from the RECETOX Centre is given in Annex 5. Contamination of the ambient air and of the indoor air is a key factor affecting health of the populations. e RECETOX researchers characterized key uncertainties affecting sampling and thereby also data interpretation and risk assessment (Melymuk et al. 2014), described the significance of the interaction of dust particles in the air with novel contaminants such as halogenated flame retardants (Okonski et al. 2014) and studied effects of particles on overall toxicity (Novák et al. 2014). e supramolecular chemistry team synthesized new macrocyclic compounds derived from bambusuril that have extraordinary properties for bonding anions (Yawer et al. 2014) or toxic chemicals (Havel et al 2014). is result creates the opportunity for practical application of the novel molecules in selective and quantitative detection of selected toxic compounds in water. 22 e photochemical group discovered a new group of fluorescent indicators having unique properties (unusually high Stokes shi and high luminosity in red and infra red areas of the spectrum) and showing a promising potential for practical use in biology (Horváth et al. 2014, Pastierik et al. 2014). ese novel chemicals were already successfully tested on myelom cells in vivo. e ecotoxicology group yielded a publication that proposes thresholds for estrogens in waste waters and further develops practical use of biodetection systems in environmental monitoring (Jarošová et al. 2014). In addition, a significant change in bioavailability (toxicity increase) of arsene species was detected during composting. is fact significantly increases risks of this metal in soils including potential contamination of the food chain (Maňáková et al. 2014). Research on sensors based on enzymes and biodegradation studies led to several excellent publications accepted in top journals – Nature Chemical Biology (Sykora et al. 2014) and in Acta Crystallographica (Chaloupková et al. 2014, Lahoda et al. 2014). All these papers described unique functional and structural determinants in the structure of the protein that influence catalytic properties of haloalkandehalogenases. e described characteristics are generally applicable and usable in protein engineering and in improving enzyme properties. Table 2. Best Research Outputs of RECETOX in 2014 (corresponding author or first author is a RECETOX employee) citation Lahoda, M., et al. 2014 Lahoda, M., Mesters, J. R., Stsiapanava, A., Chaloupkova, R., Kuty, M., Damborsky, J., Kuta Smatanova, I., 2014: Crystallographic Analysis of 1,2,3–Trichloropropane Biodegradation by Haloalkane Dehalogenase DhaA31. Acta Crystallographica D 70: 209-217. doi:10.1107/S1399004713026254 14.103 0.954 Sykora, J. et al. 2014 Sykora, J., Brezovsky, J., Koudelakova, T., Lahoda, M., Fortova, A., Chernovets, T., Chaloupkova, R., Stepankova, V., Prokop, Z., Kuta Smatanova, I., Hof, M., Damborsky, J.,2014: Dynamics and Hydration Explain Failed Functional Transformation in Dehalogenase Design. Nature Chemical Biology 10(6): 428-430. doi:10.1038/nchembio.1502 12.948 0.969 Yawer, M, et al. 2014 Yawer, M., Havel, V., Sindelar, V., A Bambusuril Macrocycle that Binds Anions in Water with High Affinity and Selectivity, Angew. Chem. Int. Eddition (2014) 276-9. DOI: 10.1002/anie.201409895 11.336 0.954 Chaloupkova, R. et al 2014 Chaloupkova, R., Prudnikova, T., Rezacova, P., Prokop, Z., Koudelakova, T., Daniel, L., Brezovsky, J., Ikeda-Ohtsubo, W., Sato, Y., Kuty, M., Nagata, Y., Kuta Smatanova, I., Damborsky, J. (2014) Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites. Acta Crystallographica D 70: 1884-1897. DOI: 10.1107/S1399004714009018 7.232 0.957 6.378 0.875 Havel, V. et al. 2014 Havel, V.; Sindelar, V; Necas M., Kaifer A. E.: Water-mediated inclusion of benzoates and tosylates inside the bambusuril macrocycle. Chem. Commun., 2014, 1372 – 1374.DOI: 10.1039/c3cc47828a impact factor percentile authors in the field Novak, J., et al. 2014 Novak, J., Hilscherová, K., Landlová, L., Čupr, P., Kohút, L., Giesy, J.P., Klánová, J.(2014). Composition and effects of inhalable size fractions of atmospheric aerosols in the polluted atmosphere. Part II. In vitro biological potencies. Environment International 63: 64–70. 6.248 0.971 Jarošová, B., et al. 2014 Jarošová, B., Bláha, L., Giesy, J.P., Hilscherová, K.(2014) What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe? Environment International 64C, 98-109.DOI:10.1016/j.envint.2013.12.009 6.248 0.971 Melymuk et al Lisa Melymuk, Pernilla Bohlin, Ondřej Sáňka, Karla Pozo, and Jana Klánová, Current challenges in air sampling of semi-volatile organic contaminants: sampling artifacts and their influence on data comparability. Environ. Sci. Technol. DOI: 10.1021/ es502164r 5.257 0.967 Okonski et al Okonski, K., Degrendele, C., Melymuk, L., Landlová, L., Kukučka, P., Vojta, Š., Kohoutek, J., Čupr, P., and Klánová, J. Particle Size Distribution of Halogenated Flame Retardants and Implications for Atmospheric Deposition and Transport, Environ. Sci. Technol. 2014 Dec 16;48(24) p.: 14426-34. doi: 10.1021/es5044547 5.257 0.967 Maňáková et al. 2014 Maňáková, B., Kuta, J., Svobodová, M., Hofman, J. (2014) Effects of combined composting and vermicomposting of waste sludge on arsenic fate and bioavailability. Journal of Hazardous Materials 280: 544-551, DOI: 10.1016/j.jhazmat.2014.08.024 4.331 0.984 Pastierik et al 2014 Pastierik T., Šebej P., Medalová J., Štacko P., Klán P. Near-Infrared Fluorescent 9-Phenylethynylpyronin Analogues for Bioimaging. J. Org. Chem. 2014, 79, 3374-3382. h¡p://pubs.acs.org/doi/abs/10.1021/jo500140y 4.564 0.825 Horváth et al 2014 Horváth, P., Šebej, P., Šolomek, T.,Klán, P., Small-Molecule Fluorophores with Large Stokes Shis: 9-Iminopyronin Analogues as Clickable Tags. e Journal of organic chemistry dx.doi.org/10.1021/jo502213t 4.564 0.825 23 contract research in 2014 RECETOX held 35 contract research projects (12 international and 23 national) in 2014. International projects were granted by nine partners, while national projects had 17 funding providers; both types of contracts drew funding from the application sector (industry, regional authorities, and global enterprises/ organizations). A detailed overview of contract research is provided in Annex 4. Results of contract research are provided in technical reports as shown in Annex 5 or in the form of laboratory results (protocols). e most significant contract research projects in 2014 were ambient air, water and soil monitoring project in 15 countries in Africa and a project developing a soware tool for visualization and interpretation of the global data under the Global Monitoring Programme of the Stockholm Convention on POPs ordered by the Stockholm Convention secretariat. National contract research stands on three long term pillars – cooperation with the Ministry of the Environment of the Czech Republic in the support of implementation of multilateral environmental agreements and conventions, long term cooperation with the authorities such as the South Moravia region, the City of Brno and the Town of Napajedla, and finally with application sector such as Českomoravský Cement Ltd. and Bioster companies. e RECETOX Centre signed several cooperation agreements in 2014 – with the University of Nairobi, Kenya on regional coordination of the Global Monitoring Plan of the Stockholm Convention on POPs and support in capacity building and transfer of knowledge in Africa, with the Environmental Protection Agency in Ghana (EPA Ghana), and the long term memoranda of understanding on epidemiological studies with University College London, with the Biology Centre of the Czech Academy of Sciences and with Seconda University Di Napoli, Italy. 24 When considering contracts with the application sector, two units of the RECETOX Centre were instrumental – the National Centre for Toxic Compounds and the Stockholm Convention Regional Centre for the Capacity-building and Transfer of Technology. Experts of the Centre have been invited to assist with a number of projects identifying the scope of environmental contamination, and designing appropriate national framework and laboratory infrastructure, and have been consulted for practical solutions for environmental decontamination and remediation nationally and internationally. ey repeatedly lectured in Bosnia and Herzegovina, Brazil, Maldives, Serbia, Turkey and other countries in 2014. Experts of the Centre undertook 20 trips abroad to provide capacity building and transfer of knowledge in other countries of the Central and Eastern Europe and Asia during 2014. In addition, the RECETOX research infrastructure organizes workshops, training courses and conferences. ere were 11 meetings (nine of them were international) in 2014 that brought almost 400 participants (Czech and international researchers) to the Centre. e established international summer school on toxic compounds had 58 participants from 28 countries in 2014. Its 10th year focused on isotope specific analyses and the summer school has a total of 425 graduates from 78 countries that have enrolled the training since 2005. An overview of the events organized or co-organized by the RECEOX Centre in 2014 is provided in Annex 7. Capacity building activity – training for using passive samplers for ambient air monitoring 25 chapter eight Publication and Other Outputs e Centre published 89 papers in peer reviewed high impact international journals, with the total impact factor (IF) reaching 353.1 in 2014 and with an average IF of 3.97 per paper, as referenced in Web of Science (ISI WOS). In addition, ten other papers were published in international journals without IF, four papers in Czech journals without IF, four books (book chapters in English), one patent, two application results by the GENASIS infrastructure core facility, and 32 RECETOX reports were released, predominantly stemming from contract research. Moreover, RECETOX presented its outputs in more than 100 conference presentations, including 9 invited lectures at 25 international and 11 national conferences. in international journals increased by 30%, though the total cumulative IF value did not change. In 2013, the cumulative IF value reached the historically highest value as the Centre succeeded in publishing extraordinary research outputs in the best journals of chemical and biological fields (the sum for the three best papers reached 107.5 in 2013). Nevertheless, the average IF/paper still reached high values, as shown in Figure 7. e list of all publications, papers and other outputs of RECETOX in 2014 is provided in the Annex 5. Figure 6 shows the increasing quantity of articles/papers in international high impact journals in last five years. Furthermore, the total number of publications Figure 6. Development of publication outputs in last five years Figure 7. Quality of publication outputs in last five years 335.70 353.10 103 89 cummulative IF 77 67 51 56 60 49 39 32 20 19 22 2010 2011 11 11 2012 65 156.80 papers with IF 35 12 2013 without IF 32 14 2014 IF/paper 157.36 paper with IF 96.94 32 3.03 2010 56 2.80 2011 49 3.21 2012 65 5.16 2013 89 3.97 2014 27 In the evaluation of scientific outputs according to RVVI methodology (RIV database points) the RECETOX Centre gained 16415 points in last five years; this amount represents about 17.2% of the total performance of the Faculty of Science, Masaryk University (excluding CEITEC’s share). Table 3 shows contributions to the overall value by the leading RECETOX authors. Overview of the publication outputs by the leading authors of the Centre in 2014 is provided in the Table 4. Table 3 Leading RECETOX authors (based on the points according to the RVVI methodology) rvvi points of the researcher for recetox total rvvi points of the researcher Damborský Jiří 1 234 1 279 Lammel Gerhard 1 171 Klánová Jana Table 4. Authors with the largest number of publications with IF in 2014 (as of 25 January 2015) cumulative if 2014 number of publications with if 2014 average if/ publication in 2014 Damborský Jiří 79.7 12 6.6 1 171 Klánová Jana 49.0 12 4.1 977 977 Chaloupková Radka 47.0 6 7.8 Hilscherová Klára 720 720 Brezovský Jan 46.1 7 6.6 Prokop Zbyněk 626 626 Hilscherová Klára 41.5 11 3.8 Holoubek Ivan 552 552 Prokop Zbyněk 35.8 6 6.0 Hofman Jakub 537 537 Klán Petr 32.6 7 4.7 Bláha Luděk 528 528 Melymuk Lisa Emily 27.8 6 4.6 Heger Dominik 492 563 Kukučka Petr 26.8 8 3.4 Klán Petr 487 696 Čupr Pavel 26.7 6 4.5 Šindelář Vladimír 437 624 Bláha Luděk 26.5 8 3,3 Chaloupková Radka 421 421 Šindelář Vladimír 25.4 4 6.4 Čupr Pavel 376 376 Lammel Gerhard 20.8 6 3.5 Brezovský Jan 205 205 Nizze¡o Luca 20.6 5 4.1 Maršálek Blahoslav 199 199 Koudeláková Táňa 20.2 2 10.1 Štěpánková Veronika 19.8 2 9,9 Bohlin Pernilla 15.2 4 3.8 Kohoutek Jiří 15.0 5 3.0 Hofman Jakub 14.4 4 3.6 author 28 author Table 4. Authors with the largest number of publications with IF in 2014 (as of 25 January 2015) (continued) cumulative if 2014 number of publications with if 2014 average if/ publication in 2014 Jarošová Barbora 14.1 3 4.7 Vrana Branislav 12.0 6 2.0 Prokeš Roman 11.5 4 2.9 Mulder M.D. 10.2 3 3.4 Šebej Peter 9.2 2 4.6 Kočan Anton 6.9 2 3.5 Babica Pavel 5.3 2 2.7 Smedes Foppe 3.2 1 3.2 Maršálek Blahoslav 2.6 1 2.6 author Based on additional information, 72% of the RECETOX Centre’s publications were prepared in cooperation with a partner institution; for 53% of publications it was a university from abroad, for another 39% it was a foreign research institution. In addition, more than 70% of publications were prepared in cooperation with more than one partner institution. All of the above demonstrates the solid integration of the Centre within the international research community and research networks. Table 5 provides a further comparison of the best scientific researchers in RECETOX Centre. e table provides their individual overall performance since the beginning of their scientific career and a more concise summary of outputs within the last five years 2010–2014. 29 Table 5. Scientific potential of the leading scientists in the RECETOX Centre (as of 21 January 2015) cumulative if 2010–2014 total number of publications with if 2010–2014 average if/ publication 2010–2014 3.8 265 48 5.5 1992 4.6 194 32 6.1 14.2 2000 3.2 152 43 3.5 30 18.1 1989 2.3 33 14 2.3 1737 24 15.6 1999 2.6 142 50 2.8 108 1493 22 13.8 1988 2.6 120 28 4.3 275 90 1505 24 16.7 1996 3.1 123 39 3.1 Prokop Zbyněk 192 45 583 15 12.9 2002 4.3 104 23 4.5 Šindelář Vladimír 188 44 879 16 19.9 2001 4.3 92 19 4.8 Kočan Anton 167 67 1291 23 19.2 1985 2.5 42 13 3.3 Vrana Branislav 162 69 1204 20 17.4 1994 2.3 52 20 2.6 Maršálek Blahoslav 141 88 1293 21 14.6 1996 1.6 23 12 1.9 Nizze¡o Luca 121 31 485 14 15.6 2005 3.9 62 14 4.4 Čupr Pavel 119 37 446 13 12.0 2003 3.2 51 15 3.4 Hofman Jakub 102 37 385 12 10.4 1997 2.7 39 14 2.8 Smedes Foppe 100 39 1835 22 47.0 1976 2.6 26 7 3.7 Babica Pavel 87 31 497 16 16.0 2004 2.8 32 11 2.9 Šimek Zdeněk 57 31 196 8 6.3 1987 1.8 19 9 2.1 total cumulative if total number of publications with if hirsch index (h-index) average citations without self-citations total number of citations year of the first publication total average if/ publication Damborský Jiří 538 143 1982 30 13.8 1995 Klán Petr 375 82 1346 25 16.4 Klánová Jana 331 102 1454 26 Holoubek Ivan 298 132 2392 Bláha Luděk 294 111 Lammel Gerhard 279 Hilscherová Klára author Note: Information on the total number of publications with impact factor by individual researchers (since the beginning of their careers) and their citations were obtained from ISI WOS on 21 January 2015. e number includes Articles, Reviews, Books, Editorials and Meetings. e values of impact factors (IF) were used as follows: the 2011 IF was used for publications issued before 2012, and a relevant individual yearly edition of the IF was used for the subsequent years (2012, 2013, 2014). 30 Painting with pigments of the Earth – project SONDAR – protecting the soil 31 chapter Nine Social and Environmental Responsibility the recetox centre cares about society, the environment and current events. We employed 21 mothers of preschool children (mainly as researchers) in 2014. A job with us allows maximum flexibility in scheduling working hours and workload and thus enables their smooth return to work aer maternity leave. Support of 466 000 CZK to cover seven posts was provided by the Operational Programme Employment Human Resources (OP LZZ) in 2014 (the length of the support ranged between one and 12 months, depending on the fulfillment of the threshold criteria by individual candidates). In addition, RECETOX is also taking part in the work-life balance project for researchers. is project is also supported from OP LZZ and its main aim is to keep researchers connected with the latest developments while on maternity and child care leave (until four years of age of the child). e project has so far provided financial support of 620 000 CZK to eight mothers and one father from our employees. Moreover, our staff and their partners or spouses can also use two information brochures that describe in detail maternity and child care leave rights and rules and provide an overview of the range and type of pre-school care and facilities available in Brno. Our support is not limited to the Czech Republic territory – we provide long term support to countries of Central and Eastern Europe. We organized ten training and capacity building workshops for experts from Serbia and Bosnia and Herzegovina (five of ten took place on the RECETOX premises, the other ones were held in the experts’s home departments). ese workshops provided transfer of expertise related to sampling, sample treatment and processing in the laboratory, and hands-on training in modern analytical methods and equipment to analyze toxic chemicals in environmental matrices. e RECETOX Centre also trained decision makers on the implementation of international law and agreements related to chemicals management (eight long-term stays of our key expert in Turkey), in particular on national coordination, enforcement, information flow and reporting. Moreover, the Stockholm Convention Regional Centre have also provided Brazil with additional training on decision making, national coordination and prepared a work plan enhancing cooperation and staff experience. Finally, the project also supported a conference entitled “Balancing career and family for young researchers”. e event was held in Brno on 27 November 2014, and hosted over 100 researchers and staff from research and development fields. Further, we held a traditional Christmas charity collection associated with the preparation of non-traditional family pictures and Christmas cards inspired by our research activities this year. e collected amount of CZK 5600 was donated to a family with a disabled child. We actively participate in green transportation. We hold a DHL certificate on compensation for the environmental impact of greenhouse gas emissions from transport in 2014. 33 chapter ten recetox in the media and awards 34 e scientific, research and educational activities of the RECETOX Centre have received a positive response through the regular and quite frequent appearance of our leading researchers in the public media, especially on Czech Television, as shown in Annex 6. In 2014, there were four TV and one radio broadcasts of our Centre and nine feature articles published in print and Internet media outside of the home page of the RECETOX Centre. In addition, the home page of the RECETOX Centre published over 45 short articles on our activities and events in the news section. For more, see Events Archive at www.recetox.muni.cz. awards In early March 2014, the Czech Institute for Accreditation issued an accreditation certificate for our Trace Analytical Laboratories to perform chemical analyses of food, feeds, biological material (cellular tissues, secretions and excretions) and environmental samples (ambient and indoor air, surface waters, sediments and soils) and to analyze the following persistent organic pollutants: dibenzodioxins and furans, dioxin-like and indicator polychlorinated biphenyls and polybrominated diphenyl ethers. In May, the research team of Professor Damborský received the J.G. Mendel Prize for Outstanding Results with International Significance from the Masaryk University Rector for their research on protein stabilization by engineering of access tunnels, published in Angewandte Chemie and protected by US patent. In November, the project “Biosensor for monitoring toxic substances in the environment”, created jointly by the Loschmidt Laboratories, the Institute of Experimental Biology, and RECETOX (all from the Faculty of Science, Masaryk University) through cooperation with the companies Photon Systems Instruments (PSI) and Enantis received second place in the contest Cooperation of the Year organized by the American Chamber of Commerce in the Czech Republic and the Association for Foreign Investment, in cooperation with the Technology Agency of the Czech Republic to determine the best cooperation between companies and the research sector. e summer brought the Rudolf Lukeš Award to Professor Petr Klán, leader of the research programme Organic Photochemistry and Supramolecular Chemistry in RECETOX for his excellent and significant results at the international level in organic, bioorganic and medicinal chemistry. e award is granted by the Czech Chemical Society (expert group on organic, bioorganic and medicinal chemistry) in cooperation with the Czech chemical company Lach-Ner. In addition, the team of associated professor Vladimír Šindelář received a US patent on preparation and use of derivatives of glycoluril and Professor Jiří Damborský became Senior Editor of the international Biotechnology Journal. Moreover, young researchers were also successful – the Sigma Aldrich Prize for the best research in biochemistry and related fields was given to RECETOX Ph.D. student Pavel Dvořák (Biotechnology group of Professor Jiří Damborský) for his work on rational engineering of synthetic pathway for biodegradation of toxic environmental pollutants. e prize is granted by the Sigma-Aldrich Company Ltd. in cooperation with the Slovak Chemical Society, Czech Chemical Society, and Czech Society for Biochemistry and Molecular Biology to young researchers (students and young scientists under 35 years). And finally, RECETOX Ph.D. student Mária Chropeňová received the Best Presentation Award for Young Scientist at the international conference EMEC 15 (15th European Meeting on Environmental Chemistry). 35 chapter eleven conclusions 36 what is waiting for us in 2015? the most important event will be the next programming period of the european structural funds. e first project calls under the Operational Programme Research, Development and Education for 2014–2020 (OP VVV) will be launched in the middle of the year. ey represent a great opportunity for RECETOX to develop further new fields of research and to use the state-of-the-art research infrastructure as well as the research potential. We are aware that new research fields must reflect national and regional innovation strategies, research priorities, and EU grand challenges and social needs. Nevertheless, further development and strengthening of human resources by all available means, including recruiting new staff coming with fresh minds and ideas is our key challenge. is is in addition to ongoing redesign of our own curricula, fostering career plans and international mobility programs together with endeavours to enhance quality of our graduates. We will also look for new opportunities in international programs such as Horizon 2020 and Marie Curie Sklodowska International Training Networks. And, last but not least, new schemes and cooperation with the application sector will have to be identified. We wish to continue in our mission to build a flexible, but also confident, valuable and practical Centre that is significant within the European research area, visible on the map, and excellent in its field, absorbing new ideas and welcoming new fields and cooperation. 37 chapter twelve glossary of terms 38 AMVIS Czech-American research cooperation program BiMAT computational biology CETOCOEN (research CEntre for TOxic COmpounds in the ENvironment) – project supported by the Operational programme Research and Development for Innovation, priority axis 2 supporting establishment of the regional centre of applied research – RECETOX Centre COST international cooperation framework among experts, researchers and academia in Europe DBU doctoral scholarship programme, mobility programme between Germany and countries of Central and Eastern Europe ECEH European Centre for Environment and Health EDC endocrine disrupting chemicals EKOT ecotoxicology ELSPAC European Longitudinal Study of Pregnancy and Childhood EMEC15 15th European Meeting on Environmental Chemistry EU European Union FP7 Seventh Framework Programme for Research and Technological Development – EU instrument for funding research within 2007–2013 FTE full time equivalent GACR Czech Science Foundation GENASIS Global ENvironmental ASsessment and Information System, global environmental information system GMP (Global Monitoring Plan of the Stockholm Convention for Persistent Organic Pollutants CHŽP environmental chemistry IBA MU Institute of Biostatistics and Analyses of the Masaryk University IF impact factor ISI WoS Institute of Scientific In LZZ operational programme Human Resources and Employment MEYS MONET MU OP RDI OP EC POPs RECETOX RI RIV RVVI SAICM SCIEX SoMoPro SP TACR UN UNEP VVV WHO WOS Ministry of Education, Youth and Sports MOnitoring NETwork, ambient air passive sampling network operated by RECETOX Centre Masaryk University operational programme Research and Development for Innovation operational programme Education for Competitiveness Persistent Organic Pollutants REsearch CEntre for TOXic compounds in the environment research infrastructure Index of information on research outputs Council for research, development and innovation of the Czech Republic – expert advisory body of the Government of the Czech Republic (Rada pro výzkum, vývoj a inovace) Strategic Approach on International Chemicals Management Scientific Exchange Programme, Swiss-Czech Cooperation in science and research South Moravian Program for Distinguished Researchers – regional grant programm for international researchers for stays in institutes of the South Moravia standard projects (GACR) Technology Agency of the Czech Republic United Nations United Nations Environment Programme Operational Programme Research, Development and Education for 2014–2020 World Health Organization Web of Science (electronic academic database providing citation index and interdisciplinary indexes of scientific papers and information) 39 Annexes Annex one Organigramme and Management Structure of the RECETOX Centre organigramme Executive Board Jakub Hofman Radovan Kareš Jana Klánová director Kolegium Vojtěch Přibyla Branislav Vrana Luděk Bláha Petr Klán Jiří Damborský Kateřina Šebková Petra Přibylová Education Jana Borůvková National and Regional Centre Lenka Andrýsková Administration Petra Růžičková Research Infrastructure Trace Analytical Laboratories Environmental Information Systems Epidemiological Studies Environmental Chemistry and Modelling Ecotoxicology Photochemistry and Supramolecular Chemistry Protein engineering 41 management structure of the recetox centre top management Petra Přibylová, Ph.D. Coordinator for the Trace Analytical Laboratories core unit Tel: +420 549 493 013 [email protected] Professor Jana Klánová, Ph.D. Director of the RECETOX Centre Tel: +420 549 495 149 [email protected] Jana Borůvková, Ph.D. Coordinator for the GENASIS core unit Tel: +420 549 495 091 [email protected] Professor Luděk Bláha, Ph.D. Deputy for Research and statutory representative of the Centre Leader of the Ecotoxicology Research Programme Tel: +420 549 493 194 [email protected] Lenka Andrýsková, Ph.D. Coordinator for the ELSPAC core unit tel.: +420 549 493 079 [email protected] Associate Professor Jakub Hofman, Ph.D. Deputy for Education Tel: +420 549 494 267 [email protected] Professor Jiří Damborský, Dr. Leader of the Protein Engineering Research Programme Tel: +420 549 493 467 [email protected] Professor Petr Klán, Ph.D. Leader of the Organic Photochemistry and Supramolecular Chemistry Tel: +420 549 494 856 [email protected] Branislav Vrana, Dr. Leader of the Environment Chemistry Research Programme Tel: +420 549 494 856 [email protected] 42 management of the recetox centre Vojtěch Přibyla RECETOX Centre deputy for finance and project support Tel: +420 549 493 165 [email protected] Radovan Kareš RECETOX Centre deputy for operations and public procurement Tel: +420 549 493 007 [email protected] Kateřina Šebková, Ph.D., M. A. Director of the National Centre for Toxic Compounds and of the Stockholm Convention Regional Centre tel: +420 549 493 063 [email protected] Petra Růžičková, Ph.D. Coordinator for the use of the RECETOX research infrastructure tel: +420 549 493 123 [email protected] extended executie board Professor Jana Klánová, Ph.D. Professor Luděk Bláha, Ph.D. Professor Ivan Holoubek, CSc. Associate Professor Jakub Hofman, Ph.D. Vojtěch Přibyla Radovan Kareš Kateřina Šebková, Ph.D., M. A. Petra Růžičková, Ph.D kolegium internal members Professor Ivan Holoubek, CSc. Professor Jana Klánová, Ph.D. Professor Luděk Bláha, Ph.D. Professor Jiří Damborský, Dr. Professor Petr Klán, Ph.D. Dr. Branislav Vrana external members (extended kolegium) Professor MUDr. Martin Bareš, Ph.D. Vice-Rector for development, Masaryk University Karel Bláha, CSc., Director of the Environmental Risks and Ecological Damage Department, Ministry of Environment of the Czech Republic Associate Professor Ladislav Dušek, Dr., Director of Institute of Biostatistics and Analyses, IBA MU Professor Petr Dvořák, CSc., Vice-rector for research, Masaryk University Rostislav Fianta, Production Director of Českomoravský cement, a.s. Zdeněk Horsák, CEO of SITA CZ Associate Professor Jaromír Leichmann, Dr., Dean of the Faculty of Science, Masaryk University Martin Procházka, Technical Director of Bochemie, a.s. Dr. David Uhlíř, Deputy Director of the South Moravian Innovation Centre (JIC) Professor MUDr. Jiří Vorlíček, CSc., Director of the Masaryk Institute of Oncology Marie Zezůlková, Head of Strategy Office, City of Brno invitees to the extended kolegium Vojtěch Přibyla, RECETOX Centre deputy for finance and project support Radovan Kareš, RECETOX Centre deputy for operations and public procurement Kateřina Šebková, Ph.D., M.A., Director of the National Centre for Toxic Compounds and of the Stockholm Convention Regional Centre RNDr. Petra Růžičková, Ph.D., Coordinator for the use of the RECETOX research infrastructure 43 Annex two STAFF in 2014 professors Luděk Bláha, Ph.D. Jiří Damborský, Dr. Jiří Holčík, CSc. Ivan Holoubek, CSc. Jiří Hřebíček, CSc. Petr Klán, Ph.D. Jana Klánová, Ph.D. Gerhard Lammel, PhD. Blahoslav Maršálek, CSc. associate professors Petr Anděl, CSc. Ladislav Dušek, Ph.D. Jakub Hofman, Ph.D. Zbyněk Prokop, Ph.D. Zdeněk Šimek, CSc. Vladimír Šindelář, Ph.D. assistant professors Pavel Čupr, Ph.D. Dominik Heger, Ph.D. Klára Hilscherová, Ph.D. Jiří Jarkovský, Ph.D. Klára Komprdová, Ph.D. Jaromír Literák, Ph.D. Natália Martínková, Ph.D. assistants Michaela Bartošová researchers, technicians and administrative staff Mgr. Ondřej Adamovský, Ph.D. (researcher) Mgr. Lenka Andrýsková, Ph.D. (researcher) Miluše Antochová (cleaner) Mgr. Ondřej Audy (researcher, Ph.D. student) RNDr. Pavel Babica, Ph.D. (researcher) Mgr. Katarína Bányiová (researcher, Ph.D. student) Mgr. Daniela Baráková (researcher, Ph.D. student) Ing. Jitka Bečanová, Ph.D. (researcher) Mgr. David Bednář (researcher) Mgr. Zdenka Bednářová (researcher, Ph.D. student) Koen Beerens, PhD. (postdoc) Mgr. Martin Beníšek, Ph.D. (researcher) Mgr. Bc. Lucie Bielská, Ph.D. (researcher) Mgr. Zuzana Bílková (researcher, Ph.D. student) RNDr. Mgr. Michal BiÃner, Ph.D. (researcher) Mgr. Lucie Bláhová, Ph.D. (researcher) MUDr. Martin Bobák, M.Sc., Ph.D. (researcher) Sara Pernilla Bohlin, PhD. (postdoc) Petra Booij, M.Sc. (researcher) RNDr. Jana Borůvková, Ph.D. (researcher) Mgr. Karel Brabec, Ph.D. (researcher) Mgr. Jan Brezovský, Ph.D. (postdoc) Mgr. Miroslav Brumovský (researcher, Ph.D student) Ing. Květuše Bursová, Ph.D. (administrative staff ) Pernilla Marianne Carlsson, PhD. (researcher, postdoc) RNDr. Eliška Čechová (researcher, Ph.D. student) Mgr. Rostislav Červenka, Ph.D. (researcher) Mgr. Martina Damborská (researcher) Mgr. Lukáš Daniel (researcher) Mgr. Celine Degrendele (researcher) Mgr. Petra Dorociaková (researcher) Mgr. Pavel Dvořák (researcher, Ph.D. student) 45 Ing. Šárka Dvořáková (administrative staff – project support) Christos Efstathiou, PhD. (postdoc) Mgr. Markéta Enderesová (researcher) Mgr. Anita Érseková (researcher, Ph.D. student) Ing. Barbora Feixová (administrative staff – project support) Mgr. Pavel Friš (laboratory support staff ) RNDr. Juraj Galeta, Ph.D. (researcher) Laura Gilberg, Dr. rer. nat. (researcher – postdoc) Mgr. Jakub Gregor, Ph.D. (administrative staff ) Irena Halíková (technician) RNDr. Václav Havel (researcher, Ph.D. student) Eva Hloušková (laboratory support staff ) * Mgr. Lenka Hofmanová (administrative staff) Eva Mary Suzanne Holt, PhD. (researcher) Bc. Richard Hůlek (programmer) Ing. Martina Hvězdová (researcher, Ph.D. student) Mgr. Radka Chaloupková, Ph.D. (researcher) Mgr. Lukáš Chrást (researcher) Mgr. et Mgr. Mária Chropeňová (researcher, Ph.D. student) Martin Chyba (technician ICT) Ing. Bc. et Bc. Aneta Jackowská (researcher) Mgr. Veronika Jálová (researcher) RNDr. Barbora Jarošová, Ph.D. (researcher) Sergio Jarque Ortiz, Ph.D. (postdoc) Bc. Luboš Jílek (technical support staff ) Ing. Adam Jonáš, M.Sc. (researcher, Ph.D. student) Mgr. Tereza Kalábová (researcher) Mgr. et Mgr. Jiří Kalina (researcher, Ph.D. student) Mgr. Martina Kalivodová (researcher, Ph.D. student) MUDr. Vít Kandrnal (researcher) Ing. Ivona Karásková (administrative staff ) Mgr. Pavlína Karásková (researcher, Ph.D. student) Mgr. Radovan Kareš (manager, Ph.D. student) Ing. Anton Kočan, CSc. (researcher) Mgr. Ing. Jiří Kohoutek (researcher) 46 Mgr. Jiří Kohoutek, Ph.D. (researcher) Mgr. Lukáš Kohút (researcher, Ph.D. student) * Mgr. Jiří Komprda, Ph.D. (researcher) Hana Kordačová (administrative staff ) Ing. Markéta Kotlánová (technical support staff ) Mgr. Martina Krátká (researcher) Mgr. Ján Krausko (technical support staff ) Mgr. Ľubica Krausková (researcher) Eva Krejčí (laboratory support staff ) RNDr. Miroslav Kubásek, Ph.D. (researcher) Mgr. Petra Kubincová (researcher, technical support staff ) Assoc.Professor MUDr. Lubomír Kukla, CSc. (researcher) Mgr. Petr Kukučka, Ph.D. (postdoc) RNDr. Petr Kulhánek, PhD. (researcher) Mgr. Jan Kuta (researcher, Ph.D. student) Mgr. Hana Lišková (researcher, Ph.D. student) Roswita Lišková (laboratory support staff ) Mgr. Veronika Lišková (researcher) Mgr. Tomáš Lízal (researcher) Mgr. Lucie Ludvíková (researcher) Mgr. Petra Macíková (researcher, Ph.D. student) Mgr. Blanka Maňáková (researcher) Sérgio Manuel Marques, PhD. (researcher) Mgr. Marek Martínek (researcher, Ph.D. student) Stanislav Mazurenko (researcher) Lisa Emily Melymuk, Ph.D. (postdoc) RNDr. Ondřej Mikeš, Ph.D. (researcher) MVDr. Přemysl Mikula, Ph.D. (researcher) * RNDr. Veronika Mlčáková, Ph.D. (administrative staff ) Mgr. Hana Moskalíková (technician) Marie Daniëlle Mulder, M.Sc. (researcher, Ph.D. student) MUDr. L‘ubica Murínová, PhD. (researcher) Mgr. Anežka Nečasová (researcher) Mgr. Petra Netroufalová (researcher, Ph.D. student) Luca NizzeÃo, PhD. (researcher) Mgr. Jiří Novák, Ph.D. (researcher) Bc. Rudolf Novák (programmer) * RNDr. Kateřina Nováková, Ph.D. (researcher) Mgr. Markéta Novotná (researcher, Ph.D. student) * Mgr. Monika Novotná (administrative staff, technical support staff) Mgr. Krzysztof Okonski (researcher, Ph.D. student) * Bc. Jana Oudová (administrative staff ) Eduardo Palao Utiel, M.Sc. (researcher) Mgr. Marek Pernica (researcher, Ph.D. student) Mgr. Eliška Petulová (technician) Mgr. Hynek Pikhart, Ph.D., M.Sc. (researcher) Mgr. Pavel Piler (researcher, Ph.D. student) Mgr. Iva Poláková (researcher) Jana Popovičová (cleaner) Karla Andrea Pozo, PhD. (researcher) RNDr. Roman Prokeš (researcher, Ph.D. student) Mgr. Bc. Tomáš Pruša (researcher) Mgr. Vojtěch Přibyla (manager) RNDr. Petra Přibylová, Ph.D. (researcher) Debajyoti Ray, Ph.D., M.Sc. (postdoc) Mgr. Pavel RoÃer (researcher, Ph.D. student) Tatsiana Rusina, Ph.D. (postdoc) RNDr. Petra Růžičková, Ph.D. (coordinator of the research infrastructure) Mgr. Jan Sadílek (reseaercher) Ing. Milan Sáňka, Dr. (researcher) Mgr. Ondřej Sáňka (researcher, Ph.D. student) Ing. Eva Sáňková (administrative staff ) RNDr. Marta Seifertová (researcher, Ph.D. student) Foppe Smedes (researcher) * Mgr. Soňa Smetanová (researcher, Ph.D. student) Ing. Marie Smutná, Ph.D. (postdoc) * RNDr. Iva Sovadinová, Ph.D. (researcher) Mgr. Kateřina Staňo Kozubík, Ph.D. (researcher) Mgr. Markéta Svobodová (researcher) Mgr. Eliška Sychrová (researcher, Ph.D. student) Ing. Michal Šalko (programmer) Mgr. Peter Šebej, Ph.D. (postdoc) Ing. Kateřina Šebková, Ph.D., M.A. (manager) Mgr. Lucie Šindelářová (researcher, Ph.D. student) * Mgr. Klára Šmídová, Ph.D. (researcher) Mgr. Tomáš Šolomek (researcher, Ph.D. student) Mgr. Irena Štěpaníková, Ph.D. (researcher) Mgr. Jakub Štěpán (researcher, Ph.D: student) Mgr. Veronika Štěpánková, Ph.D. (researcher) Ing. Zuzana Šudíková (researcher, Ph.D. student) Mgr. Marek Šudoma (researcher) Mgr. Jan Švancara (data analyst) Lýdia Tupová (technical support staff ) Mgr. Katarína Tvarůžková (technical support staff ) Mgr. Lukáš Ustrnul (researcher, Ph.D. student) Ing. Filip Vaculovič (administrative staff ) Mgr. Pavel Vaňáček (technical support staff ) RNDr. Lenka Vaňková (researcher, Ph.D. student) Mgr. Jana Vašíčková (researcher, Ph.D. student) Ing. Helena Vaverková (Šebestová) (administrative staff ) Mgr. Andrea Vítečková Wünschová, Ph.D. (researcher) Ing. Šimon Vojta, Ph.D. (researcher) Ing. Branislav Vrana (researcher) Dr. Mirza Arfan Yawer (postdoc) Anna Zelmer (researcher, Ph.D. student) Mgr. Bc. Filip Zlámal (researcher) Mgr. Radka Zounková, Ph.D. (researcher) Jaroslava Žaludová (administrative staff ) * maternity leave or child care leave 47 annex three graduates in majors guaranteed by the recetox centre in 2014 48 bachelor degree in special biology, speciation ecotoxicology family name name supervisor paper/thesis title Gaiduschová Daniela Associate Professor Ing. Josef Elster, Ph.D. Cryopreservation of plants Hon Radim RNDr. Pavel Babica, Ph.D. Impedance-based cellular assays for cell biology and in vitro toxicology Klímová Hana Mgr. Radka Zounková, Ph.D. Antibiotics and antimicrobial chemotherapeutics in the environment Lačňák Jonáš Mgr. Radka Zounková, Ph.D. Ionic liquids and their potential impact on the environment Musilová Veronika RNDr. Mgr. Michal Bi¡ner, Ph.D. New mechanisms of endocrine disruption – disruption of thyroid and glucocorticoid system Rozmánková Eliška Associate Professor RNDr. Jakub Hofman, Ph.D. Use of basic microbial parameters for bioindication of soil quality and degradation Šafaříková Eva Mgr. Andrea Vítečková Wünschová, Ph.D. Toxin influence on metabolic pathways in model systems Šmíd Jindřich RNDr. Kateřina Nováková, Ph.D Influence of external factors and different cultivation processes on production of biologically active compounds by cyanobacteria nad algae Šulc Libor Ing. Marie Smutná, Ph.D. Cyanobacterial retinoids compounds bachelor degree in chemistry, bachelor thesis completed in the recetox centre family name name supervisor paper/thesis title Fišerová Petra Ing. Jiří Kohoutek Instrumental methods for determination of retinoids in environmental samples Gáborová Romana Associate Professor RNDr. Zdeněk Šimek, CSc. Methods of sampling and treatment of water samples for the determination of steroids in the aquatic environment Hájková Lenka RNDr. Jindřich Petrlík Organochlorine Pesticides (OCPs) and PCBs in Sediments and Fish from Rivers in the Czech republic Hejduková Martina Mgr. Dominik Heger, Ph.D. Luminescence Study of Ice Komancová Lucie Ing. Branislav Vrana Method development for sampling of persistent organic compounds in the water/air surface microlayer Kuklíková Šárka Ing. Branislav Vrana Monitoring of the fate of pharmaceuticals in the wastewater treatment process Lesniáková Romana Ing. Milan Sáňka, Dr. Factors influencing contents and distribution of risk elements and risk substances in Fluvisols 49 bachelor degree in chemistry, bachelor thesis completed in the recetox centre (continuation) family name name supervisor paper/thesis title Martiník Jakub Mgr. Jan Kuta Single extraction schemes for determination of arsenic species in sediments and soils Micháliková Lucia RNDr. Jindřich Petrlík Destruction Efficiency or Irreversible Transformation Efficience of POPs in Wastes – Evaluation of Different Technologies Nežiková Barbora RNDr. Lenka Vaňková, Ph.D. Comparison of XAD resin and polyurethane foam used for air sampling and wet deposition Smatanová Jana Ing. Zdeněk Horsák, Ph.D. Drivex dosing to waste incineration proces at SITA CZ hazardous waste incenerator plant in Ostrava Svatoň Karel Professor RNDr. Petr Klán, PhD. Photochemical transformations of organic pollutants in snow Václavíková Ilona RNDr. Pavel Čupr, Ph.D. Air pollution by persistent organic pollutants in Czech Republic and Austria Žážová Daniela Ing. Jitka Bečanová, Ph.D. Occurrence of pharmaceuticals in the aquatic environment bachelor degree in experimental biology, computational biology major 50 family name name supervisor paper/thesis title Bílková Anna Mgr. Eva Budinská, Ph.D. Identification of genes predictive for response to chemotherapy in colorectal carcinoma of stage II from gene expression data. DuÑová Tereza RNDr. Eva Janoušová Pa¡ern recognition methods for image data analysis Hostýnková Ludmila RNDr. Tomáš Pavlík, Ph.D. Identification and modelling of time to relapse and progression in cancer patients using real-world hospital data Krpenská Michaela RNDr. Ondřej Májek, Ph.D. Use of control charts in performance monitoring of medical screening Mádrová Markéta Ing. Vlad Popovici, M.Sc., Ph.D. Predictive models for neoadjuvant chemotherapy response in patients with breast cancer Seňová Viktória RNDr. Jiří Jarkovský, Ph.D. Analýza antropometrických charakteristik členů rodin v dlouhodobém sledování na základě databáze ELSPAC Szolgayová Zuzana Mgr. Natália Martínková, Ph.D. Laboratory experiment design for phylogeny reconstruction of bats with geomycosis based on selected genes Volšička Vít Ing. Milan Blaha, Ph.D. Full-text search in medical reports Vozáriková Kristína Mgr. Natália Martínková, Ph.D. Signal for selection in coding DNA sequence Závala Jan Mgr. Natália Martínková, Ph.D. Pruning inconsistent fossil dates from dating divergence events in voles master degree in special biology, ekotoxicology family name name supervisor paper/thesis title Dydowiczová Aneta Mgr. Jiří Novák, Ph.D. Male reproductive system and environmental pollution Fojt Pavel Associate Professor RNDr. Jakub Hofman, Ph.D. Etotoxicity assessment with terrestrial gastropods Johnová Jitka Associate Professor RNDr. Jakub Hofman, Ph.D. Contamination of fluvisols and its effectcs on soil biological quality Kolářová Edita Mgr. Radka Zounková, Ph.D. Research of effects of veterinary pharmaceuticals in aquatic environment Krausová Zuzana RNDr. Iva Sovadinová, Ph.D. Testicular steroidogenesis and the impact of environemental contaminants Křepelková Šárka Mgr. Stanislav Malý, Ph.D. Ecotoxicity soil bioassays for evaluation of effects of digestates on agricultural soil Lenčešová Zuzana RNDr. Pavel Babica, Ph.D. Chemopreventive effects of phytochemicals – in vitro evaluation Mikulášková Lenka Mgr. Klára Hilscherová, Ph.D. Toxic effects and biochemical changes aer inhalation exposure to nanoparticles Pípal Marek Professor RNDr. Luděk Bláha, Ph.D. Danio rerio embryo model for evaluation of important micropollutants in the environment Šalplachtová Zuzana RNDr. Mgr. Michal Bi¡ner, Ph.D. Use of in vitro biotest CAFLUX in assessment of environmental contamination master degree in chemistry, environmental chemistry major family name name supervisor paper/thesis title Belháčová Michaela Ing. Branislav Vrana Measurement of POPs concentrations in pore water of sediment by passive sampling Brunnerová Petra Ing. Branislav Vrana Method development on passive sampling of POPs in mussel/fish tissue to estimate the internal chemical activity Hořínek Vít Ing. Milan Sáňka, Dr. Level and sources of diffuse contamination of forest soil by risk elements Markechová Zuzana Mgr. Jaromír Literák, Ph.D. Uptake of vapours of orgnic compounds by growing ice crystals Nagyová Michaela Ing. Jitka Bečanová, Ph.D. Landfills monitoring Poloucká Petra Associate Professor RNDr. Zdeněk Šimek, CSc. e study of alkylphenols in water 51 master degree in chemistry, environmental chemistry major (continuation) family name name supervisor paper/thesis title Procházková Tereza Mgr. Jiří Kohoutek, Ph.D. Development and validation of methods for analysis of phytoestrogens and other biologicaly active cyanobacterial metabolites Řezníková Tereza Mgr. Jaromír Literák, Ph.D. Reaction of nitrogen dioxide with soot surface and PAHs Sochorová Lenka Ing. Šimon Vojta, Ph.D. Identification of potential sources of contamination during sample preparation for the determination of selected persistent pollutants Škodová Alena Associate Professor RNDr. Zdeněk Šimek, CSc. Determination of estrogenic compounds in water using passive samplers Škopíková Iveta Ing. Branislav Vrana Study of uptake parameters of passive samplers used for monitoring of polar organic pollutants from water Vidrmanová Martina Associate Professor RNDr. Zdeněk Šimek, CSc. Methods of isolation and detection of compounds usefull as simulants of chemical warfare agents (CWA) Vyhňáková Michaela Mgr. Klára Hilscherová, Ph.D. New biodetection systems for the evaluation of estrogenic activity master degree in experimental biology, computational biology major 52 family name name supervisor paper/thesis title Hanáková Barbora Mgr. Eva Budinská, Ph.D. A gene expression perspective on the heterogeneity of KRAS mutant colorectal cancer Krupková Lenka Mgr. Klára Komprdová, Ph.D. Spatial modeling of the last-glacial vegetation of eastern-central Europe Kučerová Michaela Mgr. Karel Brabec, Ph.D. Macroinvertebrate response to stream corridors characteristics Macháčková Zita RNDr. Ondřej Májek, Ph.D. Microsimulation models in evaluation of preventive programmes cost-effectiveness Malcová Petra Professor RNDr. Jiří Hřebíček, CSc. Modelling environmental pollution in forests with the inclusion of uncertainties Ngo Ondřej RNDr. Ondřej Májek, Ph.D. Evaluation of cancer screening programmes impact Panáčková Lucie RNDr. Simona Li¡nerová Risk factors for allergy in children Svobodová Ivana RNDr. Tomáš Pavlík, Ph.D. Assessment of time-varying covariates in cancer epidemiology Uher Michal RNDr. Tomáš Pavlík, Ph.D. Using hospital-based clinical data for cancer patient surival analysis Malúšková Denisa rigorozní práce Assessment of competing risks in patients with diabetes doctoral degree in chemistry, environmental chemistry major family name name supervisor paper/thesis title Čonka Kamil Ing. Anton Kočan, CSc. Organochlorinated persistent pollutants in the environment, food and human population Degrendele Celine Professor RNDr. Jana Klánová, Ph.D. Fate of persistent organic pollutants in the atmosphere Jálová Veronika Mgr. Klára Hilscherová, Ph.D. Specific mechanisms of action of pollutant mixtures in the environment Prokeš Roman Ing. Branislav Vrana Development and characterization of new passive sampling devices for persistent organic pollutants in the aquatic environment Vaňková Lenka Professor RNDr. Jana Klánová, Ph.D. e atmospheric processes on gas/particle/water interphases doctoral degree in biology, ecotoxicology major family name name supervisor paper/thesis title Carpentier Cornelia Johanna Professor Ing. Blahoslav Maršálek, CSc. e Carpet of the Sun - On the Quantification of Algal Biomass Macíková Petra Professor RNDr. Luděk Bláha, Ph.D. Bioassays for studies of specific toxicity in mixtures of environmental contaminants Smetanová Soňa Professor RNDr. Luděk Bláha, Ph.D. Modelling of toxic effects of mixtures at different levels of biological organisation 53 chapter four research projects and contract research in 2014 54 international research projects title supervisor provider of funding timeline DENAMIC – Developmental Neurotoxicity Assessment of Mixtures in Children (7E13005) Ing. Anton Kočan, CSc. European Union / FP7 2/2012 until 12/2015 REFORM: REstoring rivers FOR effective catchment Management (282656) Mgr. Karel Brabec, Ph.D. European Union / FP7 11/2011 until 10/2015 Solutions for present and future emerging pollutants in land and water resources management (603437) Ing. Branislav Vrana European Union / FP7 10/2013 until 9/2018 Isotope forensics meets biogeochemistry – linking sources and sinks of organic contaminants by compound specific isotope investigation (264329) – CSI-Marie Curie Professor RNDr. Jana Klánová, Ph.D. European Union / FP7/Marie Curie ITN 11/2010 until 8/2015 Network for education and training for public environmental laboratories (530554-TEMPUS-1-2012-1SK-JPHES) Ing. Branislav Vrana European Union / Tempus 10/2012 until 10/2015 Erasmus Mundus – Marija Stevanovič Erasmus Mundus – Marija Stevanovič European Union / FP: Other community programs 1/2014 until 12/2014 SONDAR: Soil Strategy Network in the Danube Region – improving soil quality / efficient measures against erosion / strengthening awareness of soil / soil as an archive (M00236) Ing. Milan Sáňka, Dr. Government Office of the Lower Austria / European regional cooperation Austria – Czech Republic 2007–2013 (OP Czech Republic – Austria) 4/2012 until 6/2014 e Josef Loschmidt professor Professor Mgr. Jiří Damborský, Dr. Foundation American Jewish Joint Exposure to Endocrine-Disrupting Chemicals: Sources, Pathways, Monitoring Programs, Current Trends Ing. Kateřina Šebková, Ph.D., M.A. Světová zdravotnická organizace, ECEH, Bonn 5/2014 until 12/2014 RNDr. Pavel Čupr, Ph.D. Ministry of Regional Development/ Programme of Cooperation Slovakia– Czech Republic 2007–2013 (OP Czech Republic – Slovakia) 5/2014 until 12/2014 Needle-net (CZ/FMP/16/0379) 1/2001 until 8/2031 55 national research projects title supervisor RECETOX Networking: support for international networking of experts and Professor RNDr. Luděk Bláha, researchers in environmental research in the Czech Republic (CZ.1.07/2.3.00/20.0053) Ph.D. timeline Ministry of Education / Operational Programme Education for Competitiveness (OP EC) 6/2011 until 5/2014 National research infrastructure RECETOX (LM2011028) Professor, RNDr. Jana Klánová, Ph.D. Ministry of Education / Large Research Infrastructures for Research, Development and Innovation 1/2012 until 12/2016 Cucurbiturils and their Derivatives Allowing H-bonds Between Organic Molecules in Water (LH11012) Associate Professor, Ing. Vladimír Šindelář, Ph.D. Ministry of Education / KONTAKT II (projects starting 2011 the earliest) – AMVIS 3/2011 until 12/2014 New types of brominated flame retardants in environments, BFR-ENVI, (LH12074) Professor, RNDr. Jana Klánová, Ph.D. Ministry of Education / KONTAKT II (projects starting 2011 the earliest) – AMVIS 3/2012 until 12/2015 Novel concepts and tools for rational design of enzymes(LH14027) Ministry of Education / KONTAKT II Professor Mgr. Jiří Damborský, Dr. (projects starting 2011 the earliest) – AMVIS 4/2014 until 12/2016 Construction of a synthetic pathway for the degradation of an important environmental pollutant by protein and metabolic engineering Professor, Mgr. Jiří Damborský, Dr. Czech Science Foundation GACR/ Standard Projects 1/2012 until 12/2016 Cyanobacterial Metabolites as Potential Endocrine Disruptors (GAP503/12/0553) Mgr. Klára Hilscherová, Ph.D. Czech Science Foundation GACR/ Standard Projects 1/2012 until 12/2015 Persistent Organic Pollutants in Atmospheric Aerosols: Processes Influencing LongRange Transport in Europe (GAP503/11/1230) Professor Gerhard Lammel, PhD. Czech Science Foundation GACR/ Standard Projects 1/2011 until 12/2014 Structure-functional Relationships of Haloalkane Dehalogenases (GAP207/12/0775) Mgr. Radka Chaloupková, Ph.D. Czech Science Foundation GACR/ Standard Projects 1/2012 until 12/2016 doc. RNDr. Zdeněk Šimek, CSc. Czech Science Foundation GACR/ Standard Projects 2/2013 until 12/2016 doc. Ing. Vladimír Šindelář, Ph.D. Czech Science Foundation GACR/ Standard Projects 1/2013 until 12/2017 (GAP503/12/0572) Distribution of steroids chemicals in parts of solid environmental matrices (GA13-20357S) Synthesis and Supramolecular Characteristics of Bambusurils (GA13-15576S) 56 provider of funding title supervisor provider of funding timeline Development of Photoactivatable Compounds and of Fluorescent Markers for Chemistry and Biology (GA13-25775S) Professor, RNDr. Petr Klán, Ph.D. Czech Science Foundation GACR/ Standard Projects 1/2013 until 12/2017 Kinetics of percutaneous penetration of optical ismers of UV filters, brominated flame RNDr. Pavel Čupr, Ph.D. retardants and polar pesticides in the dermal exposure (GA14-27941S) Czech Science Foundation GACR/ Standard Projects 1/2014 until 12/2016 e transformation of mercury compounds by soil microflora: the possible use of bioremediation technologies (GAP503/12/0682) Professor RNDr. Josef Komárek, DrSc. Czech Science Foundation GACR/ Standard Projects 1/2012 until 12/2015 Cyanobacterial metabolites as potential modulators of immune system (GP13-27695P) Mgr. Ondřej Adamovský, Ph.D. Czech Science Foundation GACR/Postdoc Projects 2/2013 until 12/2015 Common species of cyanobacteria as producers teratogenic retinoids (GP14-29370P) Ing. Marie Smutná, Ph.D. Czech Science Foundation GACR/Postdoc Projects 1/2014 until 12/2016 Biosensor for monitoring of toxic compounds in the enviroment Associate Professor RNDr. Zbyněk Technological Agency of the Czech Prokop, Ph.D. Republic – programme ALFA 7/2014 until 12/2017 (TA04021380) Development and Implementation of National Monitoring Network for the Long Term Monitoring of Persistent Organic Pollutants in atmosphere of the Czech Republic by passive samplers (TB010MZP057) RNDr. Pavel Čupr, Ph.D. Technological Agency of the Czech Republic – programme BETA 1/2013 until 12/2015 Development of a system assessing spatial links of the environmental contamination (TB010MZP058) Professor RNDr. Jana Klánová, Ph.D. Technological Agency of the Czech Republic – programme BETA 1/2013 until 12/2015 Emergent pollutants in environment (TB030MZP001) Professor RNDr. Jana Klánová, Ph.D. Technological Agency of the Czech Republic – programme BETA 11/2014 until 12/2016 Effect of Floods on Soil contamination and on food chains by priority chemicals (VG20102014026) Ing. Milan Sáňka, Dr. Ministry of Interior of the Czech Republic / Program of security research 2010–2015 10/2010 until 12/2014 Assessment Methods for Assesments of the Forest Soils Burden by Priority Chemicals and Identification of Ecological Risks of the Forrest Soils contamination, KOLEP (QI112A201) Ing. Milan Sáňka, Dr. Ministry of Agriculture of the Czech Republic / Research in the agriculture complex (VAK) 1/2011 until 12/2014 Anthropogenic and Natural Drivers of Releases and Occurrence of Mixtures of Endocrine Disruptors in the Environment (ANDROMEDE) Luca Nizze¡o, Ph.D. South Moravia Region / SoMoPro 7/2013 until 6/2015 57 title supervisor provider of funding timeline Effects of organic lining materials of water pipes to the chemical burden of water (4SGA8581) Professor RNDr. Luděk Bláha, Ph.D. South Moravia Region / SoMoPro 11/2014 until 12/2016 Rational design and engineering of enzyme gates (4SGA8519) Professor Mgr. Jiří Damborský, Dr. South Moravia Region / SoMoPro 3/2014 until 12/2016 Introduction of the Principle of Species Sensitivity Distribution and Standard Tests of Sediments Toxicity in to Ecotoxicology Curricula Mgr. Zuzana Rábová Ministry of Education / Universities Development Fund 1/2013 until 5/2014 CELSPAC: Central European Longitudinal Study of Pregnacy and Childhood (MUNI/M/1075/2013), in cooperation with IBA, and FSS Professor RNDr. Jana Klánová, Ph.D. Masaryk University / research support 3/2014 until 12/2016 CHEMSOP system of laboratory analysis in environmental chemistry (MUNI/ FR/0417/2014) Mgr. et Mgr. Mária Chropeňová Masaryk University / Student projects support 3/2014 until 12/2014 Innovation of Ecotoxicology of soil microorganisms course by creating instructional videos (MUNI/FR/0210/2014) Mgr. Lucie Šindelářová Masaryk University / Student projects support 3/2014 until 12/2014 Support student research in evaluation of the environmental and health risks in 2014 (MUNI/A/0969/2013) RNDr. Pavel Čupr, Ph.D. Masaryk University / Student projects support 1/2014 until 12/2014 Support student research in ecotoxicology in 2014 (MUNI/A/0885/2013) Professor RNDr. Luděk Bláha, Ph.D. Masaryk University / Student projects support 1/2014 until 12/2014 Support student research in environmental chemistry in 2014 (MUNI/A/0968/2013) Professor RNDr. Jana Klánová, Ph.D. Masaryk University / Student projects support 1/2014 until 12/2014 Broadening and innovation aof the course “Soil Ecotoxicology” by introducing tests and training videos on biotests (MUNI/FR/0170/2014) Mgr. Lucia Škulcová Masaryk University / Student projects support 3/2014 until 12/2014 e introduction of the course „Support of publication activities for PhD. students „ (MUNI/FR/0423/2014) Professor RNDr. Luděk Bláha, Ph.D. Masaryk University / Student projects support 3/2014 until 12/2014 DENAMIC: Developmental Neurotoxicity Assessment of Mixtures in Children (282957) Ing. Anton Kočan Ministry of Education / national support 1/2012 until 12/2015 for FP7 projects (2007–2013) REFORM: REstoring rivers FOR effective catchment Management (7E12071) Mgr. Karel Brabec, Ph.D. Ministry of Education / national support 11/2011 until 10/2015 for FP7 projects (2007–2013) (FRVS/457/2013) 58 title supervisor provider of funding timeline Solutions for present and future emerging pollutants in land and water resources management Ing. Branislav Vrana Ministry of Education / national support 10/2013 until 9/2018 for FP7 projects (2007–2013) RECETOX (LO1214) Professor RNDr. Jana Klánová, Ph.D. Ministry of Education / Natinal Sustainability Programme I (LO) 1/2014 until 12/2018 title supervisor provider of funding timeline Air Monitoring Activities in Africa Professor RNDr. Jana Klánová, Ph.D. UNEP/EU 6/2014 until 6/2018 10th Summer School of Environmental Chemistry and Ecotoxicology RNDr. Petra Růžičková, Ph.D. UNEP/SSC 5/2014 until 9/2014 Global Monitoring Plan Electronic DataWarehouse – GENASIS GMP Professor RNDr. Jana Klánová, Ph.D. UNEP/SSC 4/2013 until 12/2014 Reporting to the GMP 2 on POPs levels in the Central and Eastern Europe Prof RNDr. Ivan Holoubek, CSc. UNEP/SSC 4/2013 until 12/2014 Analyses of dioxins, furans and PCB from passive sampling RNDr. Petra Přibylová, Ph.D./ Trace Analytical Laboratories Ministry of Environment, Nigeria 10/2013 until 12/2014 Analyses of PCB, BDE and organochlorine pesticides in air, water nad deposition samples from Ganges river Dr. Luca Nizze¡o / Trace Analytical Laboratories NIVA, Norway 01/2014 until 12/2014 Analyses of endocrine- and dioxin-like effects using a series of in vitro reporter gene assays Professor RNDr. Luděk Bláha, Ph.D. Chemical and Biological Monitoring in the Vicinity of Motorways – Slovakia (Ivachnová, Dubná Skala – Turany) Associate Professor RNDr. Petr contract research international contract research Anděl, CSc Universitat Tübingen, Physiologische 1/2014 until 12/2014 Ökologie der Tiere HBH Projekt spol. s r.o., Banská Bystrica 01/2014 until 12/2014 59 czech contract research title supervisor provider of funding Serving as National Centre for Persistent Organic Pollutants and Stockholm Convention Regional Centre in 2013 Ing. Kateřina Šebková, Ph.D. Ministry of the Environment, Czech Republic /Department of Environmental 1/2014 until 12/2014 Risks and Ecological Damage Providing information on chemical management for four global agreements Ing. Kateřina Šebková, Ph.D. Ministry of the Environment, Czech Republic /implementation of multilateral environmental agreements (MEAs) 6/2014 until 11/2014 Support for the ratification process of Minamata mercury convention in the Czech Republic Ing. Kateřina Šebková, Ph.D. Ministry of the Environment, Czech Republic /implementation of multilateral environmental agreements (MEAs) 6/2014 until 11/2014 Organization of the national competition synergies Ing. Kateřina Šebková, Ph.D. Ministry of the Environment, Czech Republic /implementation of multilateral environmental agreements (MEAs) 6/2014 until 11/2014 Ing. Kateřina Šebková, Ph.D. Ministry of the Environment, Czech Republic /implementation of multilateral environmental agreements (MEAs) 6/2014 until 11/2014 Ing. Kateřina Šebková, Ph.D. Ministry of the Environment, Czech Republic /implementation of multilateral environmental agreements (MEAs) 6/2014 until 11/2014 Ing. Kateřina Šebková, Ph.D. Ministry of the Environment, Czech Republic /implementation of multilateral environmental agreements (MEAs) 6/2014 until 11/2014 Ing. Kateřina Šebková, Ph.D. Ministry of the Environment, Czech Republic /implementation of multilateral environmental agreements (MEAs) 6/2014 until 11/2014 Ensuring Representation at the 10th meeting of the POPs Review Commi¡ee Ensure monitoring of POPs in biological matrices Ensuring the 3rd report on the implementation of the Stockholm Convention in the Czech Republic Specification of national information on levels of POPs in the indoor environment 60 timeline title supervisor provider of funding timeline Training representatives from Armenia, Bosnia and Herzegovina, and Moldova Support to the Implementation of the Stockhom Convention on POPs Ing. Kateřina Šebková, Ph.D Ministry of the Environment, Czech Republic /capacity building twinning projects in Central and Eastern Europe 05/2014 until 08/2014 South Moravia Region 1/2014 until 12/2014 University Ústí nad Labem 11/2014 until 12/2014 Sampling and analyses of environmental pollutants in air at selected localities of the South Moravia Region Analyses RNDr. Pavel Čupr, Ph.D./ Trace Analytical Laboratories RNDr. Pavel Čupr, Ph.D./ Trace Analytical Laboratories Support of science and technology education Trace Analytical Laboratories High school Břeclav 03/2013 until 6/2015 Sampling ambient air to establish PM10 and heavy metals, PCDDs/Fs, PCBs a indicator PCBs Professor RNDr Ivan Holoubek, CSc./ Stopová laboratoř Technická Univerzita Liberec 11/2014 until 12/2014 Cooperation in identification of chemical weapons alternatives – experimental testing and estimation of contamination risks Associate Professor RNDr. Zdeněk Šimek, CSc. SÚJCHBO - Státní ústav jaderné, chemické a biologické ochrany, v.v.i. 04/2011 until 12/2015 Air passive sampling and laboratory analyses Professor RNDr Ivan Holoubek, CSc./ Trace Analytical Laboratories Napajedla City Council 05/2013 until 12/2014 Českomoravský cement, a.s. 01/2013 until 03/2014 RNDr. P. Čupr/ Monitoring of soils and air at selected localities of Mokrá and Radotín Associate Professor J. Hofman/ Trace Analytical Laboratories Analyses RNDr. Pavel Čupr / Trace Analytical Laboratories BIOSTER, a.s. 01 until 12/2014 Analyses RNDr. Pavel Čupr / Trace Analytical Laboratories Palacký University, Olomouc 12/2014 Analyses Trace Analytical Laboratories Department of Forrest Ecology, Mendel University, Brno 9/2014 until 12/2014 POPs analysis Trace Analytical Laboratories VFU 6/2014 until 12/2014 Analyses Trace Analytical Laboratories Vodovody a kanalizace Brno 9/2014 until 12/2014 Analyses Trace Analytical Laboratories ORITEST 9/2014 until 12/2014 Chemistry course for high school teachers infrastructure /TAL Academy of Sciences Czech Republic 9/2014 until 12/2014 61 annex five publications, papers and other outputs in 2014 (as of 30 january 2015) 62 journals international papers and publications 1. Amdany R., Chimuka L., Cukrowska E., Kukučka P., Kohoutek J., Tölgyessy P. and Vrana B. (2014) Assessment of bioavailable fraction of POPS in surface water bodies in Johannesburg City, South Africa, using passive samplers: Q1 an initial assessment. Environ Monit Assess186:5639–5653. DOI 10.1007/ s10661-014-3809-3 2. Amdany R., Chimuka L., Cukrowska E., Kukučka P., Kohoutek J. and Vrana B. (2014) Investigating the temporal trends in PAH, PCB and OCP concentrations in Hartbeespoort Dam, South Africa, using semipermeable membrane devices (SPMDs). Water SA: 40/3: 425-436. h¡p://dx.doi.org/10.4314/wsa.v40i3.5 3. Ammann A. A., Macikova P., Groh K. J., Schirmer K. and Suter M. J. F. (2014). LC-MS/MS determination of potential endocrine disruptors of cortico signalling in rivers and wastewaters. Analytical and Bioanalytical Chemistry, 406(29): 7653–7665. DOI 10.1007/s00216-014-8206-9 4. Bartels-Rausch T., Jacobi H.-W., Kahan T., omas J., omson E. S., Abba¡ J., Ammann M., Blackford J. R., Bluhm H., Boxe C., Domine F., Frey M. M., Gladich I., Guzman M. I., Heger D., Huthwelker T., Klán P., Kuhs W. F., Kuo M., Maus S., Moussa S., McNeill V. F., Newberg J. T., Pe¡ersson J. B. C., Roeselova M., Sodeau J. Relationship between Snow Microstructure and Physical and Chemical Processes. Atmos. Chem. Phys. 2014, 14, 1587-1633.h¡p://www.atmos-chem-phys. net/14/1587/2014/acp-14-1587-2014.html 5. Bendl J., Stourac J., Salanda O., Pavelka A., Wieben E.D.,Zendulka J., Brezovsky J., Damborsky J., 2014: PredictSNP: Robust and Accurate Consensus Classifier for Prediction of Disease-Related Mutations. PLOS Computational Biology 10: e1003440. 6. Bidmanova, S., Hrdlickova, E., Jaros, J., Ilkovics, L., Hampl, A., Damborsky, J., Prokop, Z., 2014: Microscopic Monitoring Provides Information on Structure and Properties During Biocatalyst Immobilisation. Biotechnology Journal 9: 1-9.DOI 10.1002/biot.201300049 7. Bielská, L., Šmídová, K. and Hofman, J. (2014): Solid phase microextraction of organic pollutants from natural and artificial soils and comparison with bioaccumulation in earthworms. Ecotoxicology and Environmental Safety 100, 44-52. 8. Bláhová, L., Kohoutek, J., Lebedová, J., Bláha, L., Večeřa, Z., Buchtová, M., Míšek, I., Hilscherová, K. (2014) Simultaneous determination of reduced and oxidized glutathione in tissues by a novel liquid chromatography-mass spectrometry method: application in an inhalation study of Cd nanoparticles.Anal Bioanal Chem (2014) 406:5867-5876. DOI 10.1007/s00216-014-8033-z 9. Bohlin, P., Audy, O., Škrdlíková, L., Kukučka, P., Přibylová, P., Prokeš, R., Vojta, Š., Klánová, J.: Outdoor passive air monitoring of semivolatile organic compounds (SVOCs): a critical evaluation of performance and limitations of polyurethane foam (PUF) disks. Environ. Sci.: Processes Impacts: 16, 433-444, DOI:10.1039/C3EM00644A 63 10. Bohlin, P., Audy, O., Škrdlíková, L., Kukučka, P., Vojta, Š., Přibylová, P., Prokeš, R., Čupr, P., Klánová, J.: Evaluation and guidelines for using polyurethane foam (PUF) passive air samplers in double-dome chambers to assess semi volatile organic compounds (SVOCs) in non-industrial indoor environments. Environmental Science: Processes and Impacts (2014) Nov;16(11):2617-26 DOI: 10.1039/c4em00305e 11. Brack, W., Altenburger, R., Schüürmann, G., Krauss, M., López Herráez, D., van Gils, J., Slobodnik, J., Munthe, J., Gawlik, B. M., van Wezel, A., Schriks, M., Hollender, J., Tollefsen, K. E., Mekenyan, O., Dimitrov, S., Bunke, D., Cousins, I., Posthuma, L., van den Brink, P. J., López de Alda, M., Barceló, D., Faust, M., Kortenkamp, A., Scrimshaw, M., Ignatova, S., Engelen, G., Massmann, G., Lemkine, G., Teodorovic, I., Walz, K.-H., Dulio, V., Jonker, M. T. O., Jäger, F., Chipman, K., Falciani, F., Liska, I., Rooke, D., Zhang, X., Hollert, H., Vrana, B., Hilscherova, K., Kramer, K., Neumann, S., Hammerbacher, R., Backhaus, T., Mack, J., Segner, H., Escher, B., de Aragão Umbuzeiro, G., e SOLUTIONS project: Challenges and responses for present and future emerging pollutants in land and water resources management, Science of e Total Environment, Available online 18 June 2014, ISSN 0048-9697, h¡p://dx.doi.org/10.1016/j.scitotenv.2014.05.143. (h¡p://www.sciencedirect.com/science/article/pii/S0048969714008353) 12. Canesi L., Frenzilli G., Balbi T.,Bernardeschi M., Ciacci C., Corsolini S., Della Torre C., Fabbri R., Faleri C.,Focardi S., Guidi P., Kočan A., Marcomini A., Mario¡ini M., Nigro M., Pozo K., Rocco L., Scarcelli V., Smerilli A.,Corsi I. 2013. Interactive effects of n-TiO2 and 2,3,7,8-TCDD on the marine bivalve Mytilus galloprovincialis Original Research Article. Aquatic Toxicology, In Press, doi:10.1016/j.aquatox.2013.11.002). 13. Carvalho, R., A. Arukwe, S. Ait-Aissa, A. Bado-Nilles, S. Balzamo, A. Baun, S. Belkin, L. Blaha, F. Brion, D. Conti, N. Creusot, Y. Essig, V. Ferrero, V. FlanderPutrle, M. Fuerhacker, R. Grillari-Voglauer, C. Hogstrand, A. Jonáš, R. Loos, A.-K. Lundebye, C. Modig, P.-E. Olsson, S. Pillai, N. Polak, M. Potalivo, W. Sanchez, A. Schifferli, K. Schirmer, S. Sforzini, S. Sturzenbaum, L. Soeland, V. Turk, A. Viarengo, I. Werner, S. Yagur-Kroll, R. Zounková and T. Le¡ieri (2014). „Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?“ Toxicological Sciences. doi: 10.1093/toxsci/kfu118 14. Čonka K., Chovancová J., Stachová Sejáková Z., Dömötörová M., Fabišiková A., Drobná B., Kočan A.: PCDDs, PCDFs, PCBs and OCPs in sediments from selected areas in the Slovak Republic. Chemosphere 98 (2014), 37-43. 15. Damborsky, J., Brezovsky, J., 2014: Computational Tools for Designing and Engineering Enzymes. Current Opinion in Chemical Biology 19: 8-16. 16. Degrendele, C., Okonski, K., Melymuk, L., Landlová, L., Kukučka, P., Čupr, P., Klánová, J. (2014) Size specific distribution of the atmospheric particulate PCDD/Fs, dl-PCBs and PAHs on a seasonal scale: Implications for cancer risks from inhalation. Atmospheric Environment 98: 410-416. DOI: 10.1016/j. atmosenv.2014.09.001 17. Dvorak, P., Bidmanova, S., Damborsky, J., Prokop, Z., 2014: Immobilized Synthetic Pathway for Biodegradation of Toxic Recalcitrant Pollutant 1,2,3-Trichloropropane. Environmental Science & Technology 48(12): 6859-6866. DOI: 10.1021/es500396r 18. Dvorak, P., Kurumbang, N.P., Bendl, J., Brezovsky, J., Prokop, Z., Damborsky, J. (2014) Maximizing the Efficiency of Multienzyme Process by Stoichiometry Optimization. ChemBioChem 15(13): 1891-1895. DOI: 10.1002/cbic.201402265 64 19. Eng A., Harner T., Pozo K. 2014. A Prototype Passive Air Sampler for Measuring Dry Deposition of Polycyclic Aromatic Hydrocarbons. Environmental Science and Technology le¡ers. 1, 77-81. 20. Érseková, A., Hilscherová, K., Klánová, J., Giesy, J.P., Novák, J. (2014) Effect-based assessment of passive air samples from four countries in Eastern Europe. Environmental Monitoring and Assessment 2014 Jun;186(6):3905-16. . DOI 10.1007/s10661-014-3667-z 21. Escher, B.I., Allinson, M., Altenburger, R., Bain, P., Balaguer, P., Busch, W., Crago, J., Denslow, N.D., Dopp, E., Hilscherova, K., Humpage, A.R., Kumar, A., Grimaldi, M., Jayasinghe, B.S., Jarosova, B., Jia, A., Makarov, S., Maruya, K.A., Medvedev, A., Mehinto, A.C., Mendez, J.E., Poulsen, A., Prochazka, E., Richard, J., Schifferli, A., Schlenk, D., Scholz, S., Shiraishi, F., Snyder, S., Su, G., Tang, J.Y.M., van der Burg, B., van der Linden, S.C., Werner, I., Westerheide, S.D., Wong, C.K.C., Yang, M., Yeung, B.H.Y., Zhang, X. and Leusch, F.D.L. (2014) Benchmarking Organic Micropollutants in Wastewater, Recycled Water and Drinking Water with In Vitro Bioassays. Environmental Science and Technology 48 (3): 1940-1956. DOI:10.1021/es403899t 22. Estellano V.H., Pozo K., Silibello C., Mulder M.D., Efstathiou Ch., Tomassino M.P., Funaro F., Donadio I., Focardi, S. 2014. Characterization of urban pollution in two cities of the Puglia region in Southern Italy using field measurements and air quality (AQ) model approach. Atmospheric Pollution Research, APR 5, 34-41. doi: 10.5094/APR.2014.005 23. Ghufrana, S., Pavlova, M., Arif, M.I., Postema, C.P., Damborsky, J., Janssen, D.B. (2014) A Pseudomonas putida Strain Genetically Engineered for 1,2,3-Trichloropropane Bioremediation. Applied and Environmental Microbiology 80(17): 5467-5476. DOI: 10.1128/AEM.01620-14 24. Gielen, F., Buryska, T., Butz, M., van Vliet, L., Damborsky, J., Prokop, Z., Hollfelder, F., 2014: Interfacing Microwells with Nanoliter Compartments: A Sampler Generating High-Resolution Concentration Gradients for Quantitative Biochemical Analyses in Droplets. Analytical Chemistry 25. Gilberg, L.; Khan, S. A. M.; Enderesova, M.; Sindelar, V.: Cucurbiturils Substituted on the Methylene Bridge. Organic Le¡ers, 2014, 16, 2446 – 2449.DOI: 10.1021/ ol500828k. 26. Haeba, M., Kuta, J., Gebril, R., Awgie, W. (2014) Occurrence of Earthworms in Relation to Soil TC, TOC, TIC in Benghazi, Libya. Global Journal of Animal Scientific Research. 2(2):116-119. 27. Havel, V.; Sindelar, V; Necas M., Kaifer A. E.: Water-mediated inclusion of benzoates and tosylates inside the bambusuril macrocycle. Chem. Commun., 2014, 1372 – 1374.DOI: 10.1039/c3cc47828a 28. Hofman, J., Hovorková, I., Semple, K.T. (2014): e variability of standard artificial soils: Behaviour, extractability and bioavailability of organic pollutants. Journal of Hazardous Materials 264, 514-520, DOI:10.1016/j.jhazmat.2013.10.039 65 29. Horváth, P., Šebej, P., Šolomek, T.,Klán, P., Small-Molecule Fluorophores with Large Stokes Shis: 9-Iminopyronin Analogues as Clickable Tags. e Journal of organic chemistry dx.doi.org/10.1021/jo502213t 30. Chaloupkova, R., Prudnikova, T., Rezacova, P., Prokop, Z., Koudelakova, T., Daniel, L., Brezovsky, J., Ikeda-Ohtsubo, W., Sato, Y., Kuty, M., Nagata, Y., Kuta Smatanova, I., Damborsky, J. (2014) Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites. Acta Crystallographica D70: 1884-1897. DOI: 10.1107/S1399004714009018 31. Chavarria, M., Durante-Rodriguez, G., Krell, T., Santiago, C.,Brezovsky, J., Damborsky, J., de Lorenzo, V. (2014) Fructose 1-phosphate is the one and only physiological effector of the Cra (FruR) regulator of Pseudomonas putida. FEBS Open Bio 4: 377-386.h¡p://dx.doi.org/10.1016/j.fob.2014.03.013 32. Jacquet, R., Miège, C., Smedes, F., Tixier, C., Tronczynski, J., Togola, A., Berho, K., Valor, I., Llorca, J., Barillon, B., Marchand, P., Coquery, M. (2014) Comparison of five integrative samplers in laboratory for the monitoring of indicator and dioxin-like polychlorinated biphenyls in water. Chemosphere. DOI:10.1016/j. chemosphere.2013.09.011 33. Jancula, D., Strakova, L., Sadilek, J., Marsalek, B., Babica, P. (2014): Survey of cyanobacterial toxins in the Czech water reservoirs – the first observation of neurotoxic saxitoxins. Environmental Science and Pollution Research 21:8006–8015, DOI 10.1007/s11356-014-2699-9“ 34. Jarošová, B., Bláha, L., Giesy, J.P., Hilscherová, K. (2014) What level of estrogenic activity determined by in vitro assays in municipal waste waters can be considered as safe? Environment International 64C, 98-109.DOI:10.1016/j.envint.2013.12.009 35. Jarošová, B., Erseková, A., Hilscherová, K., Loos, R., Gawlik, B.M., Giesy, J.P., Bláha, L. (2014) Europe-wide survey of estrogenicity in wastewater treatment plant effluents: the need for the effect-based monitoring. Environmental Science and Pollution Research. 21(18):10970-10982 (DOI 10.1007/s11356-014-3056-8) 36. Jarque S., Bosch C., Grimalt J., Raldua D., Piña B. Analysis of hepatic deiodinase 2 mRNA levels in natural fish lake populations exposed to different levels of putative thyroid disrupters. Environ. Pollut. 187, 210–213 (2014) 37. Jarque S., Piña B. 2014. Deiodinases and thyroid metabolism disruption in teleost fish. Environ. Res. 135:361–375. 38. Jarque, S., Prats, E., Olivares, A., Casado, M., Ramón, M., Piña, B. (2014) Seasonal variations of gene expression biomarkers in Mytilus galloprovincialis cultured populations: Temperature, oxidative stress and reproductive cycle as major modulators. Science of the Total Environment 499: 363–372. DOI: 10.1016/j. scitotenv.2014.08.064 39. Jonáš, A., Buráňová, V., Scholz, S., Fe¡er, E., Nováková, K., Kohoutek, J., Hilscherová, K. (2015) Retinoid-like activity and teratogenic effects of cyanobacterial exudates. Aquatic Toxicology 155: 283-290. DOI: 10.1016/j.aquatox.2014.06.022 66 40. 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Kato, T., Ohshima, T., Denisenko, D., Dubovsky, P.A., Kudzej, I., Stein, W., de Miguel, E., Henden, A., Miller, I., Antonyuk, K., Antonyuk, O., Pit, N., Sosnovskij, A., Baklanov, A., Babina, J., Pavlenko, E.P., Matsumoto, K., Fukushima, D., Takenaka, M., Kawabata, M., Daisuke, D., Maeda, K., Matsuda, R., Matsumoto, K., Li¡lefield, C., Oksanen, A., Itoh, H., Masi, G., Nocentini, F., Schmeer, P., Pickard, R.D., Kiyota, S., Dvorak, S., Ulowetz, J., Maeda, Y., Michel, R., Shugarov, S.Y., Chochol, D., Novák, R. (2014) Superoutburst of SDSS J090221.35+381941.9: First Measurement of Mass Ratio in an AM CVn-Type Object using Growing Superhumps. Accepted in: Publications of the Astronomical Society of Japan (h¡p://arxiv.org/abs/1407.4196) 44. Kozlikova, B., Sebestova, E., Sustr, V., Brezovsky, J., Strnad, O., Daniel, L., Bednar, D., Pavelka, A., Manak, M., Bezdeka, M., Benes, P., Kotry, M., Gora, A., Damborsky, J., Sochor, J. (2014) CAVER Analyst 1.0: Graphic tool for interactive visualization and analysis of tunnels and channels in protein structures. Bioinformatics 30(18): 2684-2685. DOI: 10.1093/bioinformatics/btu364 45. Krausko J., Runštuk J., Neděla V., Klán P., Heger D. Observation of a Brine Layer on the Ice Surface by Environmental Scanning Electron Microscope at Higher Pressures and Temperatures. Langmuir 2014, 30, 5441–5447.h¡p://pubs.acs.org/doi/abs/10.1021/la500334e 46. Lahoda, M., Mesters, J. R., Stsiapanava, A., Chaloupkova, R., Kuty, M., Damborsky, J., Kuta Smatanova, I., 2014: Crystallographic Analysis of 1,2,3–Trichloropropane Biodegradation by Haloalkane Dehalogenase DhaA31. Acta Crystallographica D70: 209-217. doi:10.1107/S1399004713026254 47. Kurumbang, N.P., Dvorak, P., Bendl, J., Brezovsky, J., Prokop, Z.,Damborsky, J., 2014 Computer-Assisted Engineering of Synthetic Pathway for Biodegradation of Toxic Persistent Pollutant. 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Šebková, K., Gregor, J., Soukupová, M. – Závěrečná zpráva projektu „Poskytování informací o nakládání s chemickými látkami pro 4 globální úmluvy k chemickým látkám (Stockholmská, Ro¡erdamská, Basilejská a Minamatská) na jednom místě a srozumitelně pro všechny uživatele“, Centrum pro výzkum toxických látek v prostředí (RECETOX), Masarykova univerzita, Brno, listopad 2014, 31 s., RECETOX report č. 512 11. Šebková K., Andrýsková L., Pruša T., Piler P., Kohoutek J., – Závěrečná zpráva projektu „Uspořádání národní soutěže k synergiím v roce 2014“, Centrum pro výzkum toxických látek v prostředí (RECETOX), Masarykova univerzita, Brno, listopad 2014, RECETOX report č. 513 12. Šebková K., Kuta J., Literák J. – Závěrečná zpráva projektu „Podpora ratifikačního procesu Minamatské úmluvy o rtuti v České republice, zajištění účasti expertů na jednání mezivládního výboru a osvěta a vzdělávání ke rtuti v roce 2014“, Centrum pro výzkum toxických látek v prostředí (RECETOX), Masarykova univerzita, Brno, listopad 2014, RECETOX report č. 514 13. Šebková K. – Závěrečná zpráva projektu „Realizace třetí reportingové zprávy o implementaci Stockholmské úmluvy o perzistentních organických polutantech v ČR“, Centrum pro výzkum toxických látek v prostředí (RECETOX), Masarykova univerzita, Brno, září 2014, RECETOX report č. 515 14. Čupr P., Šebková K. – Závěrečná zpráva projektu „Zajištění zastoupení České republiky na 10. zasedání Výboru pro hodnocení perzistentních organických polutantů (POPRC) v roce 2014“, Centrum pro výzkum toxických látek v prostředí (RECETOX), Masarykova univerzita, Brno, listopad 2014, 80 s., RECETOX report č. 516 76 15. Přibylová P., Čupr P., Šebková K., Kohoutek ml. J., Karásková P., Prokeš R., Kohoutek st. J., Mikeš O., Klánová J.: Závěrečná zpráva projektu „Zajištění monitoringu POPs v biologických matricích a doplnění nově schválených látek do monitoringu v síti MONET v souvislosti s plněním závazků ČR Stockholmské úmluvy o perzistentních organických polutantech v roce 2014“, Centrum pro výzkum toxických látek v prostředí (RECETOX), Masarykova univerzita, Brno, listopad 2014, 74 s., RECETOX report č. 517 16. Šebková, K., Výroční zpráva o plnění předmětu smlouvy č. MŽP/750/02/CHL/08 v roce 2014, část 1, Aktivity Národního centra pro toxické látky, Centrum pro výzkum toxických látek v prostředí (RECETOX), Masarykova univerzita, Brno, listopad 2014, RECETOX report č. 518. 17. Šebková, K., Výroční zpráva o plnění předmětu smlouvy č. MŽP/750/02/CHL/08 v roce 2014, část 2, Aktivity Regionálního centra Stockholmské úmluvy o perzistentních organických polutantech, Centrum pro výzkum toxických látek v prostředí (RECETOX), Masarykova univerzita, Brno, listopad 2014, RECETOX report č. 519. 18. Šebková, K., Borůvková, J., Hůlek, R., Gregor, J., Klánová, J., Výroční zpráva o plnění předmětu smlouvy č. MŽP/750/02/CHL/08 v roce 2014, část 3, Vývoj informačního systému GENASIS, Centrum pro výzkum toxických látek v prostředí (RECETOX), Masarykova univerzita, Brno, listopad 2014, 22 s., RECETOX report č. 520. 19. Čupr, P., Prokeš, R., Přibylová, P., Kukučka, P., Kuta, J., Nečasová, A., Kohoutek, J., Klánová, J., Holoubek, I.: Dlouhodobý monitoring environmentálních polutantů ve volném ovzduší na území Jihomoravského kraje – 2014. Masarykova univerzita, RECETOX. RECETOX-TOCOEN REPORT No. 521 . Listopad 2014. 20. Holoubek, I.: Zajištění zastoupení České republiky na jednání expertních pracovních skupin pro Globální monitoring POPs (regionální skupina a globální skupina) v roce 2014. Národní POPs Centrum ČR/TOCOEN, s.r.o. Brno/RECETOX MU Brno. RECETOX-TOCOEN REPORTS No. 522, prosinec 2014, 36 s. + CD s podkladovými materiály. 77 annex six centre in the media 78 tv and radio broadcasting Znojmo mění potrubí. Je z nebezpečného olova — Regiony — ČT24, 3. červen 2014, toxikolog z Masarykovy univerzity Luděk Bláha. www.ceskatelevize.cz/.../275379-znojmo-meni-potrubi-je-z-nebezpecneho- olova/ Brněnskému ovzduší uleví ekologičtější autobusy — ČT24 — 11. červenec 2014, ředitelka Centra pro výzkum toxických látek MU Jana Klánová. m.ceskatelevize.cz/.../279910-brnenskemu-ovzdusi-ulevi-ekologictejsi- autobusy/ TV – Jana Klánová – rozhovor, Škodliviny v ovzduší, h¡p://www.ceskatelevize.cz/ivysilani/10122427178-udalosti-v-regionech-brno/ 314281381990617-udalosti-v-regionech Brno se stává metropolí vědy a výzkumu — Regiony — ČT24, 21. březen 2014 ... Brno – Centrum pro výzkum toxických látek v prostředí. www.ceskatelevize.cz/.../217919-brno-se-stava-metropoli-vedy-a-vyzkumu/ Apetýt, Brno, 13.8.2014 11:05 Setkání s Prof. Blahoslavem Maršálkem z Centra pro výzkum toxických látek v prostředí, který mimo jiné zkoumá, jak by bylo možné zlikvidovat sinice jinak, než chemicky. Výstava Urban Centrum – 18.-28.2.2014 (Stará radnice, Brno), Informace o výstavě a zmínka o RECETOX, h¡p://www.novinky.cz/vase-zpravy/jihomoravsky-kraj/brno-mesto/1796-22777-vystava-v-brnenskem-urban-centru-prozradi-kde-a-jak-se-dela-veda.html BRS Technical Assistance Newsle¡er, issue 3, July 2014, page 3 „10th RECETOX International Summer School“ Odkaz: h¡p://synergies.pops.int/ Implementation/Publications/Newsle¡er/tabid/3722/language/en-US/Default.aspx BRS Technical Assistance Newsle¡er, issue 4, August 2014, page 2 „Using GMP electronic tool“. Odkaz: h¡p://synergies.pops.int/Implementation/Publications/ Newsle¡er/tabid/3722/language/en-US/Default.aspx BRS Technical Assistance Newsle¡er, issue 6, October 2014, page 4 – announcement, Odkaz: h¡p://synergies.pops.int/Implementation/Publications/ Newsle¡er/tabid/3722/language/en-US/Default.aspx časopis Respekt h¡p://respekt.ihned.cz/c1-61545990-konec-vymluv printed journals internet magazines and newspapers special issue of the “Scientific American” journal, Czech edition, presentation of the Faculty of Science, Masaryk University including its departments Univerzita zaplatí zahraniční vědce. Napraví chybu státu, h¡p://www.online. muni.cz/udalosti/4411-univerzita-zaplati-zahranicni-vedce-napravi-chybustatu#.VKw0m00tDmQ, 26. května 2014 other media Čeští vědci zpřesnili objev nositele Nobelovy ceny v oblasti fungování enzymů, h¡p://www.veda.muni.cz/veda-a-vyzkum/4341-cesti-vedci-zpresnili-objev-nositele-nobelovy-ceny-v-oblasti-fungovani-enzymu#.VKw1H00tDmQ, 25. dubna 2014 Výstava Urban Centrum – 18-28.2.2014 (Stará radnice, Brno), Informace o výstavě a zmínka o RECETOX, h¡p://www.novinky.cz/vase-zpravy/ jihomoravsky-kraj/brno-mesto/1796-22777-vystava-v-brnenskem-urban-centru -prozradi-kde-a-jak-se-dela-veda.html Ani v Alpách není vzduch bez škodlivých látek, h¡p://www.veda.muni.cz/ veda-a-vyzkum/4201-ani-v-alplach-neni-vzduch-bez-skodlivych-latek#. VKw1mE0tDmQ, 26. února 2014 79 annex seven activities and events in 2014 80 recetox participated only number of participants (incoming only) 14. until 17. 1. 2014, Geneva, Swizerland x - closing workshop of the ArcRisk Project and ministerial conference Arctic Frontiers 2014, Tromso, Norsko 19. until 24. 1. 2014 Tromso, Norway x - 3 Masaryk University, Faculty of Science Open Door Days 18. 1. 2014 a 21. 1. 2014, Brno-Bohunice x 19 4 Training on Environmental Management CETESB, Sao Paulo, Brazil 3. until 4. 2. 2014, Sao Paulo, Brazil x - 5 Excursion to RECETOX Laboratories participants in the Chemistry Days 5. 2. 2014, RECETOX x 20 6 Training of Trainers – Turkey module 4 – BAT/BEP on POPs 17. until 19. 2. 2014, Antalya, Turecko x 35 7 Excursion to RECETOX Laboratories representative of the ScienceNet.org 19. 2. 2014, RECETOX x 1 8 Awareness raising workshop for children – Young Researcher – Ge¡ing to Know the Nature” 29. 3. 2014, RECETOX x 200 9 Lectures and Excursion to RECETOX Laboratories – Students from the Opava grammar school 11. 4. 2014, RECETOX, Brno x 23 10 Excursion to RECETOX Laboratories for secondary school students 13. until 14. 4. 2014, RECETOX, Brno x 11 SETAC Europe, Basel, Swizerland 11. until 15. 5. 2014, Basel, Swizerland 12 Day of the Science – open door day and excuseions to RECETOX laboratories 24. 5. 2014, campus Bohunice x 13 17th meeting – Council of the National Centre for Toxic Compounds, RECETOX, Brno 4. 6. 2014 RECETOX, Brno x 20 14 Excursion to RECETOX Laboratories – Biskupské gymnázium v Brně 6. 6. 2014 RECETOX, Brno x 30 15 Excursion to RECETOX Laboratories – Gymnázium Brno, Elgartova 10. 6. 2014 RECETOX, Brno x 10 16 Summer School of the Protein Engineering, Loschmidt laboratoratories, Brno 22. until 26. 6. 2014 Brno x 30 title date and venue 1 10th meeting Group on Earth Observation (GEO-X) 2 recetox organized x 81 recetox organized recetox participated only number of participants (incoming only) title date and venue 17 10th International Summer School on Toxic compounds in the Environment, RECETOX, Brno 23. until 28. 6. 2014 RECETOX, Brno x 58 18 CSI Marie Curie ITN project meeting, RECETOX, Brno 27. until 28. 6. 2014 RECETOX, Brno x 23 19 Expert meeting on Endocrine Disruptors, WHO ECEH, Bonn 7. until 8. 7. 2014, Bonn, Germany x - 20 DIOXIN 2014, 34th meeting on halogenated POPs 1. until 5. 9. 2014, Madrid, Spain x - 21 Laboratory Training for Experts from Egypt 15. until 26. 9. 2014, RECETOX, Brno x 10 22 Study Visit of Turkish Experts in the Czech Republic 21. until 27. 9. 2014, Prague a Brno, RECETOX x 11 23 Eurocities EDF Brno in RECETOX (evropská síť měst) Excursion to RECETOX Laboratories 23. 9. 2014, RECETOX, Brno x 150 24 Night of the Scientists, EXPO 2014 – human exposure 25 Meeting of the Regional organization group of the CEE region, RECETOX, Brno 6. until 7. 10. 2014, RECETOX, Brno 26 Chemical Risk Assessment Network meeting, Paris, France 8. until 10. 10. 2014, Paris, France 27 Open Science – workshop for secondary school teachers, RECETOX, Brno 20. until 24. 10. 2014, RECETOX, Brno x 20 28 DENAMIC project partner meeting, RECETOX, Brno 22. until 23. 10. 2014, RECETOX, Brno x 20 29 10th meeting of the Persistent Organic Pollutants Review Commi¡ee, POPRC10 27. until 30. 10. 2014, Rome, Italy x - 30 National Contest Synergies 2014 – online contest on chemicals and food consumption 15. 10. until 6. 12. 2014 x 142 31 18th meeting – Council of the National Centre for Toxic Compounds, Ministry of Environment, Prague 18. 11. 2014, Prague 32 6th meeting of the Intergovernmental Negotiating Committee under the Minamata Convention on Mercury 3. until 7. 11. 2014, Bangkok, ailand 82 x x 400 7 x x 0 x - recetox participated only number of participants (incoming only) 10. until 13. 11. 2014, Geneva, Switzerland x - Annual meeting of the Stockholm and Basel Convention Regional Centres 27. until 28. 11. 2014, Geneva, Switzerland x - 35 Annual meeting of the TEMPUS NETREL project partners 2. until 3. 12. 2014, RECETOX, Brno 36 Training for coordinateor of the Stockholm convention Regional Centra in Brazil (CETESB) – study visiti in the Czech Republic 2. until 5. 12. 2014, Prague and Brno 37 International workshop of the INDNOPOP project 8. until 9. 12. 2014, New Delhi, India 38 2nd meeting of the Open-Ended Working Group under SAICM 14. until 16. 12. 2014, Geneva, Switzerland title date and venue 33 Meeting of the Global Coordination Group to the GMP 34 recetox organized x 20 2 x x - 83 contacts mailing address Research Centre for Toxic Compounds in the Environment (RECETOX) Faculty of Science Masaryk University Kotlářská 267/2 611 37 Brno Czech Republic location Research Centre for Toxic Compounds in the Environment (RECETOX) University Campus Bohunice, pavilion A29 Kamenice 753/5, Brno 625 00 Brno Czech Republic website h¡p://www.recetox.muni.cz/ © All rights reserved. e material in this publication cannot be used for any other purpose without the wri¡en approval of the publisher, photos – RECETOX archive Published by RECETOX Centre as its 528th publication, March 2015 Editors: Kateřina Šebková, Petra Růžičková, Jana Klánová, Vojtěch Přibyla, Luděk Bláha, Jakub Hofman, Filip Vaculovič, Michaela Petrůjová and Lisa Melymuk (editor in chief: Kateřina Šebková) Graphic Design and Typese¡ing: Markéta Soukupová, IBA NOT FOR SALE Research Centre for Toxic Compounds in the Environment (RECETOX) University Campus Bohunice, pavilion A29 Kamenice 753/5, Brno 625 00 Brno Czech Republic h p://www.recetox.muni.cz/